Various psychiatric disorders such as major depression are associated with abnormalities in
emotional processing. Evidence indicating involvement of the endocannabinoid system in …

Humans have used Cannabis sativa (marijuana) for at least 12,000 years, but researchers
have only recently described an endogenous cannabinoid system. The endocannabinoid …

The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in
the developing central nervous system as well as playing a major role in tuning many …

Background Endocannabinoids (ECs) and related N-acyl-ethanolamides (NAEs) play
important roles in stress response regulation, anxiety and traumatic memories. In view of the …

Anxiety and trauma-related disorders are psychiatric diseases with a lifetime prevalence of
up to 25%. Phobias and post-traumatic stress disorder (PTSD) are characterized by …

The cannabinoid (CB) system is widespread in the central nervous system and is crucial for
controlling a range of neurophysiological processes such as pain, appetite, and cognition …

The cannabinoid signaling system is composed of cannabinoid (CB) receptors, their
endogenous ligands, the endocannabinoids, and the enzymes that produce and inactivate …

The cannabinoid (CB) system is a key neurochemical mediator of anxiety and fear learning
in both animals and humans. The anxiolytic effects of Δ9-tetrahydrocannabinol (THC), the …

Objectives: Cannabidiol (CBD) is a non-psychotomimetic cannabinoid compound that is
found in plants of the genus Cannabis. Preclinical research has suggested that CBD may …

Repeated injections of cannabidiol (CBD), the major non-psychotomimetic compound
present in the Cannabis sativa plant, attenuate the anxiogenic effects induced by Chronic …