Interleukin-17 promotes migration and invasion of human cancer cells through upregulation of MTA1 expression

N Guo, G Shen, Y Zhang, AA Moustafa, D Ge… - Frontiers in …, 2019 - frontiersin.org
Interleukin-17 (IL-17) has been shown to promote development of prostate, colon, skin, lung,
breast, and pancreatic cancer. The purpose of this study was to determine if IL-17 regulates …

[HTML][HTML] Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression

N Guo, J Zhang - American Journal of Cancer Research, 2022 - ncbi.nlm.nih.gov
Abstract Interleukin-17 (IL-17) has been demonstrated to promote the development of
cancer cells in most organs. The purpose of this study was to determine if IL-17 promotes the …

IL-17A promotes the migration and invasiveness of cervical cancer cells by coordinately activating MMPs expression via the p38/NF-κB signal pathway

M Feng, Y Wang, K Chen, Z Bian, J Wu, Q Gao - PLoS One, 2014 - journals.plos.org
Objective IL-17A plays an important role in many inflammatory diseases and cancers. We
aimed to examine the effect of IL-17A on the invasion of cervical cancer cells and study its …

IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells

M Wang, L Wang, T Ren, L Xu, Z Wen - Cancer Biology & Therapy, 2013 - Taylor & Francis
Osteosarcoma (OS) is the most common human primary malignant bone tumor in children
and young adults with poor prognosis because of their high metastatic potential …

[HTML][HTML] IL-17A promotes the migration and invasiveness of colorectal cancer cells through NF-κB-mediated MMP expression

H Ren, Z Wang, S Zhang, H Ma, Y Wang, L Jia… - Oncology …, 2016 - ncbi.nlm.nih.gov
Abstract Interleukin-17A (IL-17A) plays a significant role in many inflammatory diseases and
cancers. The aim of this study is to investigate the effect of IL-17A on the invasiveness of …

Effect of IL-17A on the migration and invasion of NPC cells and related mechanisms

L Wang, R Ma, Z Kang, Y Zhang, H Ding, W Guo… - PloS one, 2014 - journals.plos.org
In carcinogenesis, inflammasomes may play contradictory roles through facilitating anti-
tumor immunity or inducing oncogenic factors. Their function in cancer remains poorly …

IL-17A/IL-17RA promotes invasion and activates MMP-2 and MMP-9 expression via p38 MAPK signaling pathway in non-small cell lung cancer

Z Wu, D He, S Zhao, H Wang - Molecular and cellular biochemistry, 2019 - Springer
The present study is to investigate the effect and mechanism of action of interleukin (IL)-17A
and its receptor IL-17RA on non-small cell lung cancer (NSCLC). A total of 139 NSCLC …

Interleukin-17A promotes esophageal adenocarcinoma cell invasiveness through ROS-dependent, NF-κB-mediated MMP-2/9 activation

D Liu, R Zhang, J Wu, Y Pu, X Yin… - Oncology …, 2017 - spandidos-publications.com
Abstract Interleukin-17A (IL-17A), a pro-inflammatory cytokine secreted primarily by Th17
cells, has been proved to be involved in the microenvironment of certain inflammation …

Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression

J Li, GKK Lau, L Chen, S Dong, HY Lan, XR Huang… - PloS one, 2011 - journals.plos.org
Background IL-17A is a pro-inflammatory cytokine that plays important role in inflammatory
disease pathology and tumor microenvironment. The aim of this study is to investigate the …

Interleukin 17A promotes cell migration, enhances anoikis resistance, and creates a microenvironment suitable for triple negative breast cancer tumor metastasis

YF Tsai, CC Huang, YS Lin, CY Hsu, CP Huang… - Cancer Immunology …, 2021 - Springer
Background The aim of this study was to investigate the role of IL-17A in the cancer
microenvironment and the recurrence of triple negative breast cancer (TNBC). Methods …