The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1

CPAM Kloks, CAEM Spronk, E Lasonder… - Journal of molecular …, 2002 - Elsevier
The human Y-box protein 1 (YB-1) is a member of the Y-box protein family, a class of
proteins involved in transcriptional and translational regulation of a wide range of genes …

[HTML][HTML] Nuclear translocation of the Y-box binding protein by ultraviolet irradiation

K Koike, T Uchiumi, T Ohga, S Toh, M Wada, K Kohno… - FEBS letters, 1997 - Elsevier
The Y-box binding protein, YB-1, is a member of a DNA binding protein family with a
structurally and functionally conserved cold shock domain. Using Western blotting and …

The pleiotropic functions of the Y‐box‐binding protein, YB‐1

K Kohno, H Izumi, T Uchiumi, M Ashizuka… - …, 2003 - Wiley Online Library
The Y‐box‐binding protein (YB‐1) represents the most evolutionary conserved nucleic‐acid‐
binding protein currently known. YB‐1 is a member of the cold‐shock domain (CSD) protein …

Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation

J Zhang, JS Fan, S Li, Y Yang, P Sun… - Nucleic acids …, 2020 - academic.oup.com
Human Y-box binding protein 1 (YB-1) is a multifunctional protein and overexpressed in
many types of cancer. It specifically recognizes DNA/RNA through a cold shock domain …

[HTML][HTML] Significance of the Y-box proteins in human cancers

K Matsumoto, BH Bay - Journal of molecular and genetic medicine …, 2005 - ncbi.nlm.nih.gov
Y-box proteins belong to the cold shock domain family of proteins that are known to be
involved in both transcriptional and translational control. Here, we give a brief overview of …

Y box-binding protein-1 binds preferentially to single-stranded nucleic acids and exhibits 3′→ 5′ exonuclease activity

H Izumi, T Imamura, G Nagatani, T Ise… - Nucleic acids …, 2001 - academic.oup.com
We have previously shown that Y box-binding protein-1 (YB-1) binds preferentially to
cisplatin-modified Y box sequences. Based on structural and biochemical data, we predicted …

Structural and functional analysis of the human Y-box binding protein (YB-1) gene promoter

Y Makino, T Ohga, S Toh, K Koike… - Nucleic acids …, 1996 - academic.oup.com
We have isolated three overlapping genomic clones containing the 5′ portion of the human
YB-1 gene. These clones span∼ 25 kb of contiguous DNA containing 10 kb of 5′ flanking …

YB‐1 protein: functions and regulation

DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …

Identification and developmental characterization of a novel Y-box protein from Drosophila melanogaster

HA Thieringer, K Singh, H Trivedi… - Nucleic acids …, 1997 - academic.oup.com
The Y-box proteins are a family of highly conserved nucleic acid binding proteins which are
conserved from bacteria to human. In this report we have identified a new member of this …

An acidic protein, YBAP1, mediates the release of YB-1 from mRNA and relieves the translational repression activity of YB-1

K Matsumoto, KJ Tanaka… - Molecular and cellular …, 2005 - Am Soc Microbiol
Eukaryotic Y-box proteins are nucleic acid-binding proteins implicated in a wide range of
gene regulatory mechanisms. They contain the cold shock domain, which is a nucleic acid …