In 1970 Freedman and co-workers presented a reproducible, simple and inexpensive
animal model of endocarditis based on an insertion of an indweUingcatheter inside the …

The rate at which various antimicrobial agents eradicated Staphylococcus aureus from
cardiac vegetations in a rabbit model of endocarditis was studied. The rate at which various …

While trying to define the types of patients with positive blood cultures seen at our hospital, it
was observed that infected indwelling polyethylene catheters were one of the most common …

Antibiotic therapy for staphylococcal endocarditis is based on in vitro susceptibility, antibiotic
efficacy in experimental endocarditis, and clinical experience. Native valve endocarditis due …

Acute staphylococcal endocarditis has been produced in dogs following operative
perforation of the aortic valve and subsequent inoculation of a virulent strain of …

Endocarditis was induced in dogs with aortic insufficiency by intravenous injection of 1 ml. of
a culture of Staphylococcus aurens. Endocarditis could be prevented by a single …

Staphylococcal infective endocarditis is a severe event requiring aggressive therapy.
Antibiotic regimen depends mainly on (1) the species of Staphylococcus (Staphylococcus …

MATERIALS AND METHODS The materials and methods for the production of right and left-
sided bacterial endo-carditis have been described in detail in previous publications. 1'9 In …

We present a new experimental model of Staphylococcus aureus infective endocarditis in
guinea pigs. Permanent aortic valve damage was produced by electrocoagulation after …

A review has been made of all cases of staphylococcal endocarditis observed in this
hospital in the past 10-year period (1949 to 1958). This study reveals a significant increase …