Panaxynol induces fibroblast-like synovial cell apoptosis, inhibits proliferation and invasion through TLR4/NF-κB pathway to alleviate rheumatoid arthritis
Y Zhao, X Sun, J Lin, T Zhang, S Liu, Z Yan - International …, 2021 - Elsevier
Background and purpose Panaxynol (PAL, PubChem CID: 5281149) is a common natural
minor component in Umbelliferae plants, such as Radix Saposhnikoviae Divaricatae …
minor component in Umbelliferae plants, such as Radix Saposhnikoviae Divaricatae …
Punicalagin inhibited inflammation and migration of fibroblast-like synoviocytes through NF-κB pathway in the experimental study of rheumatoid arthritis
M Huang, K Wu, S Zeng, W Liu, T Cui… - Journal of …, 2021 - Taylor & Francis
Background The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …
Protective effects of paeonol on inflammatory response in IL-1β-induced human fibroblast-like synoviocytes and rheumatoid arthritis progression via modulating NF-κB …
K Zhai, H Duan, L Luo, W Cao, F Han, L Shan… - …, 2017 - Springer
Various investigations have demonstrated that human fibroblast-like synoviocytes
rheumatoid arthritis (HFLS-RA) take part in the chronic inflammatory responses and RA …
rheumatoid arthritis (HFLS-RA) take part in the chronic inflammatory responses and RA …
Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK …
D Cao, Q Fan, Z Li, M Chen, Y Jiang, R Lin, J Li… - Phytomedicine, 2022 - Elsevier
Background Activated fibroblast-like synoviocyte (FLS) played a significant role in the
pathogenesis and progression of rheumatoid arthritis (RA). Apigenin-4′-O-α-L-rhamnoside …
pathogenesis and progression of rheumatoid arthritis (RA). Apigenin-4′-O-α-L-rhamnoside …
Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes by inhibiting the NF‑κB and MAPK signaling …
X Gao, X Kang, H Lu, E Xue… - Molecular …, 2022 - spandidos-publications.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease that mainly targets the synovial
membrane, thus causing stiffness, deformity and dysfunction of joints. To date, no effective …
membrane, thus causing stiffness, deformity and dysfunction of joints. To date, no effective …
Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway
G Ge, J Bai, Q Wang, X Liang, H Tao, H Chen… - Science China Life …, 2022 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …
Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo …
Background Rheumatoid arthritis is a chronic and idiopathic autoimmune disorder. Perillyl
alcohol (POH) is a monoterpene which can be extracted from widely available essential oils …
alcohol (POH) is a monoterpene which can be extracted from widely available essential oils …
Anti-rheumatoid arthritis effects of flavonoids from Daphne genkwa
Y Sun, Y Bao, H Yu, Q Chen, F Lu, S Zhai… - International …, 2020 - Elsevier
Objective This study aims to select the most effective anti-Rheumatoid Arthritis (RA)
component of flavonoids from Daphne genkwa Sieb. et Zucc. by anti-inflammatory and …
component of flavonoids from Daphne genkwa Sieb. et Zucc. by anti-inflammatory and …
Anhuienoside C ameliorates collagen-induced arthritis through inhibition of MAPK and NF-κB signaling pathways
Q Liu, XH Xiao, LB Hu, HY Jie, Y Wang… - Frontiers in …, 2017 - frontiersin.org
Anemone flaccida Fr. Schmidt (Ranunculaceae)(Di Wu in Chinese) is used to treat punch
injuries and rheumatoid arthritis (RA). Our previous report has shown that crude triterpenoid …
injuries and rheumatoid arthritis (RA). Our previous report has shown that crude triterpenoid …
Liensinine inhibits IL-1β-stimulated inflammatory response in chondrocytes and attenuates papain-induced osteoarthritis in rats
L Wang, T Shao, C Liu, Z Han, S Zhang, Y Dong… - International …, 2024 - Elsevier
Osteoarthritis (OA) is a joint disease caused by inflammation of cartilage and synovial tissue.
Suppressing the process of inflammatory reaction and the generation of oxidative stress is …
Suppressing the process of inflammatory reaction and the generation of oxidative stress is …
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