Mannose-Binding Lectin Plasma Levels and Gene Polymorphisms in Plasmodium falciparum Malaria

AJF Luty, JFJ Kun, PG Kremsner - The Journal of infectious …, 1998 - academic.oup.com
The contribution of mannose-binding lectin (MBL) to protection from malaria was assessed
by comparing plasma concentrations of MBL and the frequency of MBL gene polymorphisms …

[HTML][HTML] Mannose-binding lectin variant associated with severe malaria in young African children

V Holmberg, F Schuster, E Dietz, JCS Visconti… - Microbes and …, 2008 - Elsevier
Mannose-binding lectin (MBL) is a serum protein which initiates innate immune responses
to microbial pathogens by binding to non-self surface oligosaccharides. MBL deficiency is …

Mannose-Binding Lectin Is a Disease Modifier in Clinical Malaria and May Function as Opsonin for Plasmodium falciparum- Infected Erythrocytes

P Garred, MA Nielsen, JAL Kurtzhals… - Infection and …, 2003 - Am Soc Microbiol
Variant alleles in the mannose-binding lectin (MBL) gene (mbl2) causing low levels of
functional MBL are associated with susceptibility to different infections and are common in …

Association of a new mannose-binding lectin variant with severe malaria in Gabonese children

ABW Boldt, A Luty, MP Grobusch, K Dietz, A Dzeing… - Genes & …, 2006 - nature.com
Abstract Mannose-binding lectin (MBL2) variants that decrease the plasma level of the
protein or encode dysfunctional proteins are frequently associated with the severity of a …

Recognition of Plasmodium falciparum proteins by mannan-binding lectin, a component of the human innate immune system

J Klabunde, AC Uhlemann, AE Tebo, J Kimmel… - Parasitology …, 2002 - Springer
The mannan-binding lectin (MBL) is a serum protein, which is involved in the immune
defence against viruses, bacteria and parasites. Children who have mutations in the MBL …

MBL2 Variations and Malaria Susceptibility in Indian Populations

AN Jha, P Sundaravadivel, VK Singh, SS Pati… - Infection and …, 2014 - Am Soc Microbiol
Human mannose-binding lectin (MBL) encoded by the MBL2 gene is a pattern recognition
protein and has been associated with many infectious diseases, including malaria. We …

Mannose-binding lectin and susceptibility to schistosomiasis

JS Antony, O Ojurongbe, H van Tong… - The Journal of …, 2013 - academic.oup.com
Background. Human ficolin 2 (encoded by FCN2) and mannose-binding lectin (encoded by
MBL2) bind to specific pathogen-associated molecular patterns, activate the complement …

Mannose-binding lectin alleles in sub-Saharan Africans and relation with susceptibility to infections

LE Mombo, CY Lu, S Ossari, I Bedjabaga, L Sica… - Genes & …, 2003 - nature.com
Mannose-binding lectin (MBL) plays an important role in the early stages of primary
infections and during the decay of maternal antibodies in infants. Various studies have …

Impact of mannose-binding lectin on susceptibility to infectious diseases

DP Eisen, RM Minchinton - Clinical Infectious Diseases, 2003 - academic.oup.com
When the adaptive immune response is either immature or compromised, the innate
immune system constitutes the principle defense against infection. Mannose-binding lectin …

Absence of association between mannose-binding lectin gene polymorphisms and HIV-1 infection in a Colombian population

S Malik, M Arias, C Di Flumeri, LF Garcia, E Schurr - Immunogenetics, 2003 - Springer
Mannose-binding lectin (MBL) is a calcium-dependent lectin shown to play an important role
in innate immunity to infection by activating the classical complement pathway and …