High-intensity exercise leads to a decline in muscle performance, known as fatigue. This
decline in performance is manifested in the muscles as decreased force production and …

SUMMARY 1 Muscle fatigue (ie the decrease in muscle performance during exercise) has
been studied extensively using a variety of experimental paradigms, from mouse to human …

Muscle fatigue is a complex, multifactorial process. The causes of fatigue are classified as
central, including brain and spinal cord mechanisms, and peripheral including peripheral …

The origins of fatigue during exercise have intrigued scientists for well over a century and
have proven to be a rich, but complex, area of investigation. Understanding fatigue and the …

Peripheral fatigue results from multiple electrochemical and mechanical events in the cell
body and the muscle–tendon complex. Combined force and surface electromyographic …

The depression in force and/or velocity associated with muscular fatigue can be the result of
a failure at any level, from the initial events in the motor cortex of the brain to the formation of …

Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a
constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of …

Muscle fatigue can be caused by a number of different mechanisms that result in an acute
reduction in the ability to perform a motor task. These mechanisms include the physiological …

Prolonged dynamic exercise and sustained isometric contractions induce muscle fatigue, as
manifested by decreased performance and a reduction in the maximum voluntary …

This volume describes the current state of our knowledge on the neurobiology of muscle
fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms …