Exogenous oxidative stress induces cell death, but the upstream molecular mechanisms
involved of the process remain relatively unknown. We determined the instant dynamic …

Free radicals induce oxidative stress in vivo, leading to various disorders and diseases. In
the present study, the effect of oxygen pressure on the cytotoxicity induced by free radicals …

Cerebral ischemia/reperfusion (I/R) injuries are common and often cause severe
complications. Ozone has been applied for protecting I/R injury in animal models of several …

In order to reveal neurodegeneration elicited by reactive oxygen intermediates (ROI),
neuronally differentiated cells from mouse embryonal carcinoma P19 cell line were exposed …

Oxidative stress induces apoptosis in many cellular systems including glioblastoma cells,
with caspase-8 activation was regarded as a major contribution to $ H_2O_2 $-induced cell …

Many anticarcinogenic drugs kill tumour cells by inducing apoptosis. We examined the
effects of hydrogen peroxide (H2O2) on arsenic trioxide (As2O3)‐induced cell killing. Low …

During normal cellular activities Reactive Oxygen Species (ROS) and Reactive Nitrogen
Species (RNS) are produced. In addition to beneficial functions they play a critical role in cell …

Breast cancer is one of the leading causes of mortality among women worldwide due to
aggressive behavior, early metastasis, resistance to existing chemotherapeutic agent and …

Abstract Background/Aims: Spontaneous apoptosis in culture is cell density-dependent. Yet,
little is known about the density-dependence of apoptosis induced by oxidative stress and …

Several human diseases have been associated with the overproduction of reactive oxygen
species (ROS) and subsequently various antioxidants emerged as potential therapeutic …