Reactive oxygen species including H2O2 activate an array of intracellular signalling
cascades that are closely associated with cell death and cell survival pathways. The human …

Glial cells protect themselves from the elevated reactive oxygen species (ROS) via
developing unusual mechanisms to maintain the genomic stability, and reprogramming of …

Rotenone, a commonly used pesticide, is well documented to induce selective degeneration
in dopaminergic neurons and motor dysfunction. Such rotenone-induced neurodegenration …

Doxorubicin (DOX) is a common anticancer drug. The mechanisms of DOX induced
apoptosis and the involvement of reactive oxygen species (ROS) in apoptotic signaling were …

Among the main causes of cancer cell resistance to chemotherapy are p53 mutation and
hypoxic tumor microenvironment. However, the effect of hypoxia can be very different from …

Reactive oxygen species (ROS) play an important role in cell death induced by many
different stimuli. This study shows that hydrogen peroxide-induced apoptosis in T-cells did …

The promoting effect of ethanol against the cytotoxicity of hydrogen peroxide (H2O2) in
differentiated PC12 cells was assessed by measuring the effect on the mitochondrial …

This study was designed to investigate the protective effects of extracellular superoxide
dismutase (SOD3) against hydrogen peroxide (H 2 O 2) induced damage in human …

V79C cells were derived from V79 cell line by through chronic oxidative stress that was
found to be radio-resistant. These cells had demonstrated transformation–like stable …

Aim: Arsenic trioxide (As2O3), known as pi-shuang and the most toxic compound in
traditional Chinese medicine, has been used as an antitumor agent for thousands of years …