Obesity is one of the most serious global health problems, with an incidence that increases
yearly and coincides with the development of cancer. Adipose tissue macrophages (ATMs) …

With the recognition of obesity as a global health crisis, researchers have devoted greater
effort to defining and understanding the pathophysiological molecular pathways regulating …

Inflammation has been known as one of the main keys to the establishment and progression
of cancers. Chronic low-grade inflammation is also a strategic condition that underlies the …

Obesity has emerged as a major public health concern with a staggering 39% worldwide
prevalence as of 2021. Given the magnitude of the problem and considering its association …

Introduction: Obesity has increased dramatically over the last three decades. Thus,
epidemiological evidence linking obesity and cancer has ignited our interest in the …

Recently, tumor microenvironment (TME) and its stromal constituents have provided
profound insights into understanding alterations in tumor behavior. After each identification …

The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …

Simple Summary The inflammatory adipose microenvironment in obesity plays a crucial role
in cancer development and metastases. By focusing on adipocytes and macrophages, as …

There is compelling epidemiological evidence linking obesity to many tumours; however, the
molecular mechanisms fuelling this association are not clearly understood. Emerging …

Obesity induces multifactorial effects such as dyslipidemia, insulin resistance, and arterial
hypertension that influence the progression of many diseases. Obesity is associated with an …