Obesity, a low-grade inflammatory condition, represents a major risk factor for the
development of several pathologies including colorectal cancer (CRC). Although the …

Obesity is a major driving factor in the incidence, progression, and poor treatment response
in gastrointestinal cancers. Herein, we conducted a comprehensive analysis of the impact of …

The epidemic spread of obesity is nowadays recognized as a global health and economic
burden, arising great interest in the scientific community. The rate of adult obesity steadily …

Adiposity is associated with an increased risk of various types of carcinoma. One of the
plausible mechanisms underlying the tumor-promoting role of obesity is an aberrant …

Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

The past few years have provided substantial evidence for the vital role of the local tumor
microenvironment for various aspects of tumor progression. With obesity and its …

Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable
plasticity and play pivotal roles in coordinating immune responses and maintaining tissue …

Colorectal cancer (CRC) is the third most common cancer worldwide and a leading cause of
death, with burden expected to increase in the coming years. Enhanced adiposity …

The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …