Parasitic infections are a major theme in the “hygiene hypothesis”, as allergies and
autoimmune diseases are less prevalent in countries with higher burdens of helminths and …

Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Worldwide, more than a billion people are infected with helminths. These worm infections
generally do not lead to mortality, however, they are chronic in nature and can lead to …

Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …

There is increasing interest in helminth parasite modulation of the immune system, both from
the fundamental perspective of the “arms race” between host and parasite, and equally …

Helminths are master regulators of host immune responses utilising complex mechanisms to
dampen host protective Th2‐type responses and favour long‐term persistence. Such …

Helminths are multicellular eukaryotic parasites that infect over one quarter of the world's
population. Through coevolution with the human immune system, these organisms have …

Helminth parasites are complex metazoans that belong to different taxonomic families but
that collectively share the capacity to downregulate the host immune response directed …

The field of infectious disease immunology is at an exciting intersection with new concepts in
immune regulation meeting with the dynamics of infectious diseases. We discuss how the …