MiR-335-5p inhibits β-amyloid (Aβ) accumulation to attenuate cognitive deficits through targeting c-jun-N-terminal kinase 3 in Alzheimer's disease
D Wang, Z Fei, S Luo, H Wang - Current neurovascular …, 2020 - ingentaconnect.com
Objective: Alzheimer's disease (AD), also known as senile dementia, is a common
neurodegenerative disease characterized by progressive cognitive impairment and …
neurodegenerative disease characterized by progressive cognitive impairment and …
miR-485-5p alleviates Alzheimer's disease progression by targeting PACS1
C He, C Su, W Zhang, Q Wan - Translational Neuroscience, 2021 - degruyter.com
Alzheimer's disease (AD) is a common dementia and a heterogeneous disease. Previous
research has validated that microRNAs (miRNAs) are pivotal regulators in the initiation and …
research has validated that microRNAs (miRNAs) are pivotal regulators in the initiation and …
miR-23b-3p rescues cognition in Alzheimer's disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways
H Jiang, J Liu, S Guo, L Zeng, Z Cai, J Zhang… - … Therapy-Nucleic Acids, 2022 - cell.com
Dysregulated microRNA (miRNA) expression in the brain can contribute to cognitive
dysfunction and aberrant tau hyperphosphorylation in Alzheimer's disease (AD). Several …
dysfunction and aberrant tau hyperphosphorylation in Alzheimer's disease (AD). Several …
MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein …
W Wan, G Liu, X Li, Y Liu, Y Wang, H Pan, J Hu - Bioengineered, 2021 - Taylor & Francis
Alzheimer's disease (AD) is a progressive neurodegenerative disease. Multiple reports have
elucidated that microRNAs are promising biomarkers for AD diagnosis and treatment …
elucidated that microRNAs are promising biomarkers for AD diagnosis and treatment …
MicroRNA-128 knockout inhibits the development of Alzheimer's disease by targeting PPARγ in mouse models
Y Liu, Y Zhang, P Liu, H Bai, X Li, J Xiao, Q Yuan… - European journal of …, 2019 - Elsevier
Alzheimer's disease (AD) is a great threat for the health and life of elderly people. MicroRNA-
128 (miR-128) has been reported to be abnormally expressed in the brain of AD patients …
128 (miR-128) has been reported to be abnormally expressed in the brain of AD patients …
[HTML][HTML] MicroRNA-511-3p regulates Aβ1–40 induced decreased cell viability and serves as a candidate biomarker in Alzheimer's disease
T Wang, W Zhao, Y Liu, D Yang, G He, Z Wang - Experimental Gerontology, 2023 - Elsevier
Background Alzheimer's disease (AD) is a progressive neurodegenerative disease with high
incidence in the elderly population. MicroRNAs have been reported to abnormally …
incidence in the elderly population. MicroRNAs have been reported to abnormally …
MicroRNA-22-3p ameliorates Alzheimer's disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus
P Xia, J Chen, Y Liu, X Cui, C Wang, S Zong… - Journal of …, 2022 - Springer
Background Studies have suggested that many down-regulated miRNAs identified in the
brain tissue or serum of Alzheimer's disease (AD) patients were involved in the formation of …
brain tissue or serum of Alzheimer's disease (AD) patients were involved in the formation of …
Targeting MicroRNA-485-3p blocks Alzheimer's disease progression
HS Koh, SJ Lee, HJ Lee, JW Min, T Iwatsubo… - International journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a form of dementia characterized by progressive memory
decline and cognitive dysfunction. With only one FDA-approved therapy, effective treatment …
decline and cognitive dysfunction. With only one FDA-approved therapy, effective treatment …
MicroRNA‐128 suppresses tau phosphorylation and reduces amyloid‐beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's …
Abstract Introduction and Aims Alzheimer's disease (AD) is characterized by the abnormal
accumulation of hyperphosphorylated tau proteins and amyloid‐beta (Aβ) peptides. Recent …
accumulation of hyperphosphorylated tau proteins and amyloid‐beta (Aβ) peptides. Recent …
MicroRNA-107 ameliorates damage in a cell model of Alzheimer's disease by mediating the FGF7/FGFR2/PI3K/Akt pathway
W Chen, L Wu, Y Hu, L Jiang, N Liang, J Chen… - Journal of Molecular …, 2020 - Springer
Abstract Alzheimer's disease (AD), the most prevalent representation of dementia, is a
neurodegenerative disease resulting from the degenerative disturbance of the central …
neurodegenerative disease resulting from the degenerative disturbance of the central …