The first step in the clinical approach to patients with metabolic acidosis is to deal with
emergencies and to anticipate and prevent dangers associated with therapy. The traditional …

Clinicians should identify life-threatening issues in patients with metabolic acidosis. These
threats may be present before therapy begins and/or anticipated after therapy commences …

Metabolic acidosis is defined as a low arterial blood pH in conjunction with a reduced serum
bicarbonate concentration,[HCO3−]. Respiratory compensation results in a decrease in …

Metabolic acidosis is noted in the majority of patients with chronic kidney disease (CKD)
when glomerular filtration rate (GFR) decreases to less than 20% to 25% of normal, although …

When a strong acid is added to plasma, one expects a quantitative relationship between
excess anion gap (ΔAG) and bicarbonate deficit (ΔHCO 3−) with the ΔAG/ΔHCO 3− ratio …

Metabolic acidosis is a common, but not invariable, feature of chronic kidney disease. Serum
[HCO3 À] varies widely, but the average value typically falls as serum creatinine …

Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO3−)
concentration, a secondary decrease in the arterial partial pressure of carbon dioxide …

The common approach to the differential diagnosis of metabolic acidosis is to divide the
patients into two catego ries based on whether the anion gap in plasma is increased or not …

Metabolic acidosis with an increased anion gap (AG) is frequently seen among patients with
end-stage renal failure that is corrected to a variable degree by chronic hemodialysis. The …

Metabolic acidosis has been recently recognized as an important comorbid event in the high
mortality rates seen in patients with end-stage renal disease. The recognition of …