Current state of theranostics in metastatic castrate‐resistant prostate cancer
Prostate cancer remains one of the leading causes of cancer‐related death in the world.
There have been significant advances in chemotherapy, hormonal therapy and targeted …
There have been significant advances in chemotherapy, hormonal therapy and targeted …
The role of theranostics in prostate cancer
Theranostics in men with metastatic castration-resistant prostate cancer (mCRPC) has been
developed to target bone and the tumor itself. Currently, bone-directed targeted alpha …
developed to target bone and the tumor itself. Currently, bone-directed targeted alpha …
A treatment paradigm shift: targeted radionuclide therapies for metastatic castrate resistant prostate cancer
Simple Summary Metastatic prostate cancer has traditionally been treated with a
combination of hormonal and chemotherapy regimens. With the recent FDA approval of …
combination of hormonal and chemotherapy regimens. With the recent FDA approval of …
The Outcome and Safety of Re-challenge Lutetium-177 PSMA (177Lu-PSMA) Therapy with Low-Dose Docetaxel as a Radiosensitizer—a Promising Combination in …
M Maharaj, L Heslop, T Govender, N Korowlay… - Nuclear Medicine and …, 2021 - Springer
Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (PSMA-RLT) with
lutetium-177 (177 Lu-PSMA) has been used in metastatic castrate-resistant prostate cancer …
lutetium-177 (177 Lu-PSMA) has been used in metastatic castrate-resistant prostate cancer …
Evaluation of the tolerability and safety of [225Ac]Ac-PSMA-I&T in patients with metastatic prostate cancer: a phase I dose escalation study
S Ling, AAM van der Veldt, M Konijnenberg, M Segbers… - BMC cancer, 2024 - Springer
Background Life expectancy of patients with metastatic castration-resistant prostate cancer
(mCRPC) is still limited despite several systemic treatments. Within five years after diagnosis …
(mCRPC) is still limited despite several systemic treatments. Within five years after diagnosis …
Third-line treatment and 177Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review
FE von Eyben, G Roviello, T Kiljunen… - European journal of …, 2018 - Springer
Aims There is a controversy as to the relative efficacy of 177 Lu prostate specific membrane
antigen (PSMA) radioligand therapy (RLT) and third-line treatment for patients with …
antigen (PSMA) radioligand therapy (RLT) and third-line treatment for patients with …
Results of a 50 patient single-center phase II prospective trial of Lutetium-177 PSMA-617 theranostics in metastatic castrate-resistant prostate cancer.
228 Background: Lutetium-177 (177Lu)-PSMA-617 (LuPSMA) is a radiolabelled small
molecule that binds with high affinity to prostate specific membrane antigen (PSMA) …
molecule that binds with high affinity to prostate specific membrane antigen (PSMA) …
Advances in 177Lu-PSMA and 225Ac-PSMA Radionuclide Therapy for Metastatic Castration-Resistant Prostate Cancer
SW Ling, E de Blois, E Hooijman, A van der Veldt… - Pharmaceutics, 2022 - mdpi.com
For patients with metastatic castration-resistant prostate cancer (mCRPC), the survival
benefit of classic treatment options with chemotherapy and drugs targeting androgen …
benefit of classic treatment options with chemotherapy and drugs targeting androgen …
Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic …
177Lu-PSMA-617 is a radioligand with high affinity for prostate-specific membrane antigen
(PSMA), enabling targeted β-irradiation of prostate cancer. We have previously reported …
(PSMA), enabling targeted β-irradiation of prostate cancer. We have previously reported …
Lutetium-177 PSMA for the treatment of metastatic castrate resistant prostate cancer: a systematic review
Introduction Metastatic castrate resistant prostate cancer (mCPRC) remains an aggressive
form of prostate cancer that no longer responds to traditional hormonal treatment alone …
form of prostate cancer that no longer responds to traditional hormonal treatment alone …