MicroRNA delivery for regenerative medicine

B Peng, Y Chen, KW Leong - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNA (miRNA) directs post-transcriptional regulation of a network of genes by targeting
mRNA. Although relatively recent in development, many miRNAs direct differentiation of …

MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells

SG Ong, WH Lee, K Kodo, JC Wu - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) are key components of a broadly conserved post-transcriptional
mechanism that controls gene expression by targeting mRNAs. miRNAs regulate diverse …

Scaffold‐based microRNA therapies in regenerative medicine and cancer

CM Curtin, IM Castaño… - Advanced healthcare …, 2018 - Wiley Online Library
Abstract microRNA‐based therapies are an advantageous strategy with applications in both
regenerative medicine (RM) and cancer treatments. microRNAs (miRNAs) are an …

A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and …

IM Castaño, CM Curtin, G Shaw, JM Murphy… - Journal of controlled …, 2015 - Elsevier
Manipulation of gene expression through the use of microRNAs (miRNAs) offers
tremendous potential for the field of tissue engineering. However, the lack of sufficient site …

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …

miRNA delivery by nanosystems: state of the art and perspectives

FC Moraes, C Pichon, D Letourneur, F Chaubet - Pharmaceutics, 2021 - mdpi.com
MicroRNAs (miRNAs) are short (~ 21–23 nucleotides), non-coding endogenous RNA
molecules that modulate gene expression at the post-transcriptional level via the …

[HTML][HTML] MicroRNAs as novel regulators of stem cell fate

E Choi, E Choi, KC Hwang - World journal of stem cells, 2013 - ncbi.nlm.nih.gov
Mounting evidence in stem cell biology has shown that microRNAs (miRNAs) play a crucial
role in cell fate specification, including stem cell self-renewal, lineage-specific differentiation …

[HTML][HTML] Role of microRNAs in progenitor cell commitment and osteogenic differentiation in health and disease

MT Valenti, L Dalle Carbonare… - … Journal of Molecular …, 2018 - spandidos-publications.com
MicroRNAs (miRNAs) are considered 'micro-managers of gene expression'and awareness
of their fundamental role in the control of biological functions is constantly increasing. Bone …

Recent progress in microRNA-based delivery systems for the treatment of human disease

Y Fu, J Chen, Z Huang - ExRNA, 2019 - Springer
MicroRNAs (miRNAs) are naturally occurring, small non-coding RNAs that mediate
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …

Recent advances in miRNA delivery systems

I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
MicroRNAs (miRNAs) represent a family of short non-coding regulatory RNA molecules that
are produced in a tissue and time-specific manner to orchestrate gene expression post …