Monitoring spiking activity across large neuronal populations at behaviorally relevant
timescales is critical for understanding neural circuit function. Unlike calcium imaging …

Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising
approach for understanding the role of large cortical networks in the neural coding of …

Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …

Understanding information processing in the brain requires monitoring neuronal activity at
high spatiotemporal resolution. Using an ultrafast two-photon fluorescence microscope …

Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling
the function of neuronal circuits but is challenging due to the limited performance of existing …

Two-photon voltage imaging has long been heralded as a transformative approach capable
of answering many long-standing questions in modern neuroscience. However, exploiting …

Optical interrogation of voltage in deep brain locations with cellular resolution would be
immensely useful for understanding how neuronal circuits process information. Here, we …

To better understand the input-output computations of neuronal populations, we developed
ArcLight-ST, a genetically-encoded voltage indicator, to specifically measure subthreshold …

Two-photon imaging of bulk-loaded calcium dyes can record action potentials (APs)
simultaneously from dozens of spatially resolved neurons in vivo. Extending this technique …

The ability to probe the membrane potential of multiple genetically defined neurons
simultaneously would have a profound impact on neuroscience research. Genetically …