Placental malaria infections are caused by Plasmodium falciparum–infected red blood cells
sequestering in the placenta by binding to chondroitin sulfate A, mediated by VAR2CSA, a …

Malaria during pregnancy causes serious disease that is associated with sequestration in
the placenta of Plasmodium falciparum infected erythrocytes that adhere to several host …

Background Malaria in pregnancy is characterized by accumulation of infected erythrocytes
(IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium …

Infection with Plasmodium falciparum during pregnancy is one of the major causes of
malaria related morbidity and mortality in newborn and mothers. The complications of …

Background Pregnant women are infected by Plasmodium falciparum with novel antigenic
phenotypes that adhere to chondroitin sulfate A (CSA) and other receptors in the placenta …

Sequestration of Plasmodium falciparum‐infected erythrocytes in the placenta is responsible
for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result …

Background The var2csa gene encodes a Plasmodium falciparum adhesion receptor which
binds chondroitin sulfate A (CSA). This var gene is more conserved than other PfEMP1/var …

Cytoadhesion of infected red blood cells (iRBC) is mediated through parasite‐encoded,
clonally variant surface antigens (VSA) and is a central process in the pathogenesis of …

Pregnancy-associated malaria (PAM) arises from sequestration of Plasmodium falciparum-
parasitized erythrocytes (PE) in the placenta, leading to chronic symptoms in the expectant …

During pregnancy, specific variants of Plasmodium falciparum-infected erythrocytes (IEs)
can accumulate in the placenta through adhesion to chondroitin sulfate A (CSA) mediated …