Kidney perfusion: some like it hot others prefer to keep it cool

I Jochmans, ML Nicholson… - Current Opinion in Organ …, 2017 - journals.lww.com
A great deal of research is still needed to optimize and logistically place hypothermic and
normothermic perfusion technologies. In the future, we may progress toward organ-tailored …

Advances in hypothermic and normothermic perfusion in kidney transplantation

TB Smith, ML Nicholson, SA Hosgood - Transplantology, 2021 - mdpi.com
Hypothermic and normothermic machine perfusion in kidney transplantation are purported
to exert a beneficial effect on post-transplant outcomes compared to the traditionally used …

Normothermic machine perfusion of the kidney: better conditioning and repair?

SA Hosgood, E van Heurn… - Transplant …, 2015 - Wiley Online Library
Kidney transplantation is limited by hypothermic preservation techniques. Prolonged periods
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival …

Normothermic ex vivo kidney perfusion for the preservation of kidney grafts prior to transplantation

JM Kaths, VN Spetzler, N Goldaracena… - JoVE (Journal of …, 2015 - jove.com
Kidney transplantation has become a well-established treatment option for patients with end-
stage renal failure. The persisting organ shortage remains a serious problem. Therefore, the …

Ex-vivo normothermic perfusion in renal transplantation: past, present and future

C Yong, SA Hosgood, ML Nicholson - Current Opinion in Organ …, 2016 - journals.lww.com
In the last 5 years, normothermic perfusion has been translated from an experimental
laboratory technique into clinical practice with promising results. Normothermic perfusion …

Normothermic ex vivo kidney perfusion for human kidney transplantation: first North American results

LI Mazilescu, P Urbanellis, SJ Kim, T Goto… - …, 2022 - journals.lww.com
Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

[HTML][HTML] Normothermic kidney perfusion: An overview of protocols and strategies

TR Elliott, ML Nicholson, SA Hosgood - American Journal of …, 2021 - Elsevier
Normothermic machine perfusion (NMP) technologies are emerging as an important adjunct
in organ preservation and transplantation. NMP can enable the reduction or avoidance of …

Dissemination of a novel organ perfusion technique: ex vivo normothermic perfusion of deceased donor kidneys

P Chandak, BL Phillips, R Uwechue… - Artificial …, 2019 - Wiley Online Library
Ex vivo normothermic perfusion (EVNP) technology is a promising means of organ
preservation, assessment, and preconditioning prior to kidney transplantation, which has …

[HTML][HTML] Improved normothermic machine perfusion after short oxygenated hypothermic machine perfusion of ischemically injured porcine kidneys

S Lignell, S Lohmann, KM Rozenberg… - Transplantation …, 2021 - journals.lww.com
Background. In an era where global kidney shortage has pushed the field of transplantation
towards using more marginal donors, modified kidney preservation techniques are currently …

[HTML][HTML] Subnormothermic oxygenated perfusion optimally preserves donor kidneys ex vivo

RN Bhattacharjee, A Ruthirakanthan, Q Sun… - Kidney International …, 2019 - Elsevier
Introduction The current methods of preserving donor kidneys in nonoxygenated cold
conditions minimally protect the kidney against ischemia-reperfusion injury (IRI), a major …