Sweet Dopamine: Sucrose Preferences Relate Differentially to Striatal D2 Receptor Binding and Age in Obesity

MY Pepino, SA Eisenstein, AN Bischoff, S Klein… - Diabetes, 2016 - Am Diabetes Assoc
Alterations in dopaminergic circuitry play a critical role in food reward and may contribute to
susceptibility to obesity. Ingestion of sweets releases dopamine in striatum, and both sweet …

Striatal dopamine D2-like receptor correlation patterns with human obesity and opportunistic eating behavior

J Guo, WK Simmons, P Herscovitch, A Martin… - Molecular …, 2014 - nature.com
The obesity epidemic is believed to be driven by a food environment that promotes
consumption of inexpensive, convenient, high-calorie, palatable foods. Individual …

[HTML][HTML] Dopamine signaling in food addiction: role of dopamine D2 receptors

JH Baik - BMB reports, 2013 - ncbi.nlm.nih.gov
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors

ND Volkow, GJ Wang, F Telang, JS Fowler, PK Thanos… - Neuroimage, 2008 - Elsevier
Dopamine's role in inhibitory control is well recognized and its disruption may contribute to
behavioral disorders of discontrol such as obesity. However, the mechanism by which …

Imaging of brain dopamine pathways: implications for understanding obesity

GJ Wang, ND Volkow, PK Thanos… - Journal of addiction …, 2009 - journals.lww.com
Obesity is typically associated with abnormal eating behaviors. Brain imaging studies in
humans implicate the involvement of dopamine (DA)-modulated circuits in pathologic eating …

Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index

SA Eisenstein, AN Bischoff, DM Gredysa… - Scientific reports, 2015 - nature.com
PET studies have provided mixed evidence regarding central D2/D3 dopamine receptor
binding and its relationship with obesity as measured by body mass index (BMI). Other …

The role of dopamine in motivation for food in humans: implications for obesity

GJ Wang, ND Volkow, JS Fowler - Expert opinion on therapeutic …, 2002 - Taylor & Francis
Obesity is a major public health problem. The increasing number of obese individuals in the
US adds urgency to the efforts to understand the mechanisms underlying pathological …

Striatal dopamine transporter availability is not associated with food craving in lean and obese humans; a molecular imaging study

J van Son, KA van Galen, AM Bruijn, KE Koopman… - Brain sciences, 2021 - mdpi.com
Brain dopamine signaling is essential for the motivation to eat, and obesity is associated
with altered dopaminergic signaling and increased food craving. We used molecular …

Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in‐vivo μPET imaging ([11C] raclopride) and in‐vitro ([3 …

PK Thanos, M Michaelides, YK Piyis, GJ Wang… - Synapse, 2008 - Wiley Online Library
Introduction: Dopamine (DA) regulates food intake by modulating food reward and
motivation but its involvement in obesity is much less understood. Recent evidence points to …

Dopamine D2/3 receptor availability and amphetamine-induced dopamine release in obesity

E van de Giessen, F Celik… - Journal of …, 2014 - journals.sagepub.com
Introduction: The neurotransmitter dopamine is important in the regulation of food intake. It is
hypothesised that obese people experience less reward from food due to lower striatal …