[HTML] mdpi.com

[HTML][HTML] Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)

X Xie, D Frank, PK Patnana, J Schütte… - International Journal of …, 2021 - mdpi.com
Growth Factor Independence 1 (GFI1) is a transcription factor with an important role in the
regulation of development of myeloid and lymphoid cell lineages and was implicated in the …
被引用次数：2 相关文章 所有 15 个版本

Anti-cancer effects of curcumin on myelodysplastic syndrome through the inhibition of enhancer of zeste homolog-2 (EZH2)

L Ma, X Zhang, Z Wang, L Huang… - Current Cancer Drug …, 2019 - ingentaconnect.com
Background: Enhancer of zeste homolog-2 (EZH2), a histone methyltransferase that
regulates histone H3 methylation of lysine27 (H3K27me3), is involved in the pathogenesis …
被引用次数：13 相关文章 所有 3 个版本
[HTML] sciencedirect.com

[HTML][HTML] GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome

L Botezatu, LC Michel, H Makishima, T Schroeder… - Experimental …, 2016 - Elsevier
Highlights•GFI1 36N is present in about 9%–12% of all Caucasian patients with
myelodysplastic syndrome.•GFI1 36N is an independent, adverse prognostic factor for …
被引用次数：16 相关文章 所有 12 个版本
[HTML] frontiersin.org

[HTML][HTML] Role of GFI1 in epigenetic regulation of MDS and AML pathogenesis: mechanisms and therapeutic implications

T Möröy, C Khandanpour - Frontiers in Oncology, 2019 - frontiersin.org
Growth factor independence 1 (GFI1) is a DNA binding zinc finger protein, which can
mediate transcriptional repression mainly by recruiting histone-modifying enzymes to its …
被引用次数：25 相关文章 所有 5 个版本
[PDF] academia.edu

GFI1 as a novel prognostic and therapeutic factor for AML/MDS

JM Hönes, L Botezatu, A Helness, C Vadnais… - Leukemia, 2016 - nature.com
Genetic and epigenetic aberrations contribute to the initiation and progression of acute
myeloid leukemia (AML). GFI1, a zinc-finger transcriptional repressor, exerts its function by …
被引用次数：47 相关文章 所有 8 个版本
[HTML] sciencedirect.com

[HTML][HTML] Gfi136N as a novel marker and therapeutic target of MDS and AML

LC Michel, L Botezatu, JM Hönes, A Marneth… - Blood, 2014 - Elsevier
Abstract Growth Factor Independence 1 (GFI1) is a hematopoietic transcription factor that
plays a crucial role in the development of myeloid precursor cells. Its variant single …
被引用次数：2 相关文章 所有 2 个版本
[HTML] sciencedirect.com

[HTML][HTML] Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML

L Botezatu, LC Michel, A Helness, C Vadnais… - Experimental …, 2016 - Elsevier
Highlights•The GFI1 36N variant accelerates development of acute myeloid leukemia in
acute myeloid leukemia/myelodysplastic syndrome mouse models.•GFI1 36N induces …
被引用次数：18 相关文章 所有 9 个版本

GFI1b as a novel oncosuppressor in AML

A Thivakaran, L Botezatu, JM Hoenes, YS Al-Matary… - 2016 - ashpublications.org
The proper differentiation of hematopoietic stem cells (HSCs) is regulated by a concert of
different so called transcription factors (TFs). A disturbed function of these TFs can be the …
被引用次数：1 相关文章 所有 2 个版本
[HTML] nih.gov

[HTML][HTML] Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome

A Thivakaran, L Botezatu, JM Hönes, J Schütte… - …, 2018 - ncbi.nlm.nih.gov
Differentiation of hematopoietic stem cells is regulated by a concert of different transcription
factors. Disturbed transcription factor function can be the basis of (pre) malignancies such as …
被引用次数：25 相关文章 所有 7 个版本
[PDF] exphem.org

Growth factor independence 1 (Gfi1) regulates the AML supporting function of mesenchymal stromal cells

C Khandanpour - Experimental Hematology, 2017 - exphem.org
Background: Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are
hematopoetic disorders, which affect the myeloid lineages of hematopoiesis. Both are …
被引用次数：2 相关文章