Magnesium nebulization utilization in management of pediatric asthma (MagNUM PA) trial: study protocol for a randomized controlled trial

S Schuh, J Sweeney, SB Freedman, AL Coates… - Trials, 2016 - Springer
Background Up to 30% of children with acute asthma are refractory to initial therapy, and
84% of this subpopulation needs hospitalization. Finding safe, noninvasive, and effective …

Nebulized magnesium for moderate and severe pediatric asthma: a randomized trial

K Alansari, W Ahmed, BL Davidson… - Pediatric …, 2015 - Wiley Online Library
Background Intravenous magnesium sulfate, a rescue therapy added to bronchodilator and
systemic steroid therapy for moderate and severe asthma, is uncommonly administered. We …

Effect of nebulized magnesium vs placebo added to albuterol on hospitalization among children with refractory acute asthma treated in the emergency department: a …

S Schuh, J Sweeney, M Rumantir, AL Coates… - Jama, 2020 - jamanetwork.com
Importance While intravenous magnesium decreases hospitalizations in refractory pediatric
acute asthma, it is variably used because of invasiveness and safety concerns. The benefit …

Optimizing the use of intravenous magnesium sulfate for acute asthma treatment in children

X Liu, T Yu, JE Rower, SC Campbell… - Pediatric …, 2016 - Wiley Online Library
Background Asthma is the most common pediatric chronic disease and currently affects 7.1
million children in the United States. Many children experience acute asthma exacerbations …

Intravenous magnesium in asthma pharmacotherapy: variability in use in the PECARN registry

MD Johnson, JJ Zorc, DS Nelson, TC Casper… - The Journal of …, 2020 - Elsevier
Objective To examine the use, efficacy, and safety of intravenous magnesium sulfate (IVMg)
in children with asthma whose emergency department (ED) management is recorded in the …

Systematic review on efficacy of magnesium (intravenous or nebulized) for acute asthma episodes in children

JL Mathew, M Walia - Indian pediatrics, 2017 - Springer
This systematic review and meta-analysis aimed to evaluate the efficacy of intravenous (IV)
and nebulized magnesium sulfate for acute asthma in children. Ten randomized and quasi …

Intravenous magnesium and hospital outcomes in children hospitalized with asthma

JW Antoon, M Hall, V Mittal, K Parikh… - Hospital …, 2021 - publications.aap.org
BACKGROUND Use of intravenous magnesium (IVMg) for childhood asthma exacerbations
has increased significantly in the last decade. Emergency department administration of IVMg …

Prospective observational study of clinical outcomes after intravenous magnesium for moderate and severe acute asthma exacerbations in children

DH Arnold, W Gong, JW Antoon, LB Bacharier… - The Journal of Allergy …, 2022 - Elsevier
Background There is limited knowledge regarding whether intravenous magnesium (IV-Mg)
improves outcomes in children with acute asthma exacerbations. Objective To examine …

Intravenous and nebulized magnesium sulfate for treating acute asthma in children: a systematic review and meta-analysis

Z Su, R Li, Z Gai - Pediatric emergency care, 2018 - journals.lww.com
Objective This study aimed to evaluate the efficacy of intravenous (IV) and nebulized
magnesium sulfate in acute asthma in children. Methods The PubMed, Cochrane Library …

Association between intravenous magnesium therapy in the emergency department and subsequent hospitalization among pediatric patients with refractory acute …

S Schuh, SB Freedman, R Zemek, AC Plint… - JAMA Network …, 2021 - jamanetwork.com
Importance Despite guidelines recommending administration of intravenous (IV) magnesium
sulfate for refractory pediatric asthma, the number of asthma-related hospitalizations has …