[HTML][HTML] Piecing it together: atrophy profiles of hippocampal subfields relate to cognitive impairment along the Alzheimer's disease spectrum

NJ Christopher-Hayes, CM Embury… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction People with Alzheimer's disease (AD) experience more rapid declines in their
ability to form hippocampal-dependent memories than cognitively normal healthy adults …

[HTML][HTML] Atrophy of hippocampal subfields relates to memory decline during the pathological progression of Alzheimer's disease

Y Xiao, Y Hu, K Huang… - Frontiers in Aging …, 2023 - frontiersin.org
Background It has been well documented that atrophy of hippocampus and hippocampal
subfields is closely linked to cognitive decline in normal aging and patients with mild …

Differential annualized rates of hippocampal subfields atrophy in aging and future Alzheimer's clinical syndrome

L Nadal, P Coupé, C Helmer, JV Manjon, H Amieva… - Neurobiology of …, 2020 - Elsevier
Several studies have investigated the differential vulnerability of hippocampal subfields
during aging and Alzheimer's disease (AD). Results were often contradictory, mainly …

Longitudinal trajectory of Amyloid‐related hippocampal subfield atrophy in nondemented elderly

L Zhang, E Mak, A Reilhac, HY Shim… - Human brain …, 2020 - Wiley Online Library
Hippocampal atrophy and abnormal β‐Amyloid (Aβ) deposition are established markers of
Alzheimer's disease (AD). Nonetheless, longitudinal trajectory of Aβ‐associated …

[HTML][HTML] Multimodal magnetic resonance imaging reveals distinct sensitivity of hippocampal subfields in asymptomatic stage of Alzheimer's disease

J Wu, SS Shahid, Q Lin, A Hone-Blanchet… - Frontiers in aging …, 2022 - frontiersin.org
While hippocampal atrophy and its regional susceptibility to Alzheimer's disease (AD) are
well reported at late stages of AD, studies of the asymptomatic stage of AD are limited but …

Hippocampal subregions are differentially affected in the progression to Alzheimer's disease

SJ Greene, RJ Killiany… - … Record: Advances in …, 2012 - Wiley Online Library
Atrophy within the hippocampus (HP) as measured by magnetic resonance imaging (MRI) is
a promising biomarker for the progression to Alzheimer's disease (AD). Subregions of the …

[HTML][HTML] Trajectories of the hippocampal subfields atrophy in the Alzheimer's disease: a structural imaging study

W Zhao, X Wang, C Yin, M He, S Li… - Frontiers in …, 2019 - frontiersin.org
Background The hippocampus and hippocampal subfields have been found to be diversely
affected in Alzheimer's Disease (AD) and early stages of Alzheimer's disease by …

Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia

ME Dounavi, E Mak, K Wells, K Ritchie, CW Ritchie… - Neurobiology of …, 2020 - Elsevier
The hippocampus is one of the first regions to demonstrate atrophy during the prodromal
stage of Alzheimer's disease. Volumetric analysis of its individual subfields could provide …

Amyloid burden in cognitively normal elderly is associated with preferential hippocampal subfield volume loss

PJ Hsu, H Shou, T Benzinger, D Marcus… - Journal of …, 2015 - content.iospress.com
The earliest sites of brain atrophy in Alzheimer's disease are in the medial temporal lobe,
following widespread cerebral cortical amyloid deposition. We assessed 74 cognitively …

[HTML][HTML] Relationship between hippocampal subfield volumes and cognitive decline in healthy subjects

S Doran, D Carey, S Knight, JF Meaney… - Frontiers in Aging …, 2023 - frontiersin.org
We examined the relationship between hippocampal subfield volumes and cognitive decline
over a 4-year period in a healthy older adult population with the goal of identifying subjects …