Abstract Objectives The Swedish Family-Cancer Database has been the major source of
population-based prospective data on familial risks on most cancers, including prostate …

INTRODUCTION: Family history of prostate cancer is an established risk factor for prostate
cancer. However, the relationship between family history of cancers other than prostate …

PURPOSE To determine if familial prostate cancer patients have a less favorable prognosis
than patients with sporadic prostate cancer after treatment for localized disease with either …

Objectives To compare traditional prognostic characteristics of familial vs sporadic prostate
cancers and to investigate potential detection biases arising from differences in the use of …

Objectives. Several studies have identified prostate cancer family history as a risk factor for
prostate cancer incidence, typically associated with a twofold to fourfold increase in risk. A …

Purpose: Breast and prostate cancer co-occur in families, and women with a family history of
prostate cancer are at increased breast cancer risk. Prostate cancer is among the most …

Background Family history is a strong risk factor for prostate cancer. The aim of this study
was to investigate whether increased diagnostic activity is related to the incidence of …

Purpose: Family history of prostate cancer is one of the few universally accepted risk factors
for prostate cancer. How much an assessment of inherited polygenic risk for prostate cancer …

Current epidemiologic and genetic data suggest the hypothetical paradigm that prostate
cancer occurs in three forms: sporadic, familial, and hereditary (Figure 1). Sporadic cases …

Prostate cancer (PCa) has a large familial component, but understanding of its genetic basis
is fragmentary. Breast cancers may be associated with PCa, but whether this is true for other …