In a population‐based case‐control study of prostate cancer conducted in Montreal, Toronto
and Vancouver between 1989 and 1993, a total of 640 newly incident cases and 639 aged …

Genetic predisposition accounts for≥ 10% of all cancer of the prostate (CaP) and is
therefore considered a major risk factor, together with age and ethnic origin. Several …

BACKGROUND It seems unlikely that the large ethnic differences in prostate cancer risk can
be explained completely by ethnic differences in diet or other lifestyle characteristics …

There is a familial aggregation of prostate cancer, and 5 to 10% of all prostate cancers are
estimated to be inherited in an autosomal‐dominant mode. A population‐based cohort study …

It has been suggested that positive family history constitutes a risk factor for the development
of prostate cancer. Familial clustering of prostate cancer might suggest that genetic factors …

Positive family history of prostate cancer (PCa) has been consistently associated with
increased PCa risk [1]. It is widely used in clinical practice and is a strong indication …

OBJECTIVE To identify published studies quantifying familial prostate cancer risks in
relatives of prostate cancer cases and, by meta‐analysis, obtain more precise estimates of …

Background Recent literature highlights the importance of germline genetic testing in
prostate cancer (PCa) patients. Surprisingly, a literature review indicates that family history …

Nieder AM, Taneja SS, Zeegers MPA and Ostrer H. Genetic counseling for prostate cancer
risk. Clin Genet 2003: 63 169‐176.© Blackwell Munksgaard, 2003 Major risk factors for …

BACKGROUND One of the difficulties confronting genetic studies of prostate cancer is the
complex and heterogeneous etiology. Given the high population frequency of lesions …