Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …

The present article describes the synthesis, in vitro urease inhibition and in silico molecular
docking studies of a novel series of bi-heterocyclic bi-amides. The synthesis of title …

In an attempt to achieve a new class of phosphoramide inhibitors with high potency and
resistance to the hydrolysis process against urease enzyme, we synthesized a series of …

A urease inhibitor with good in vivo profile is considered as an alternative agent for treating
infections caused by urease-producing bacteria such as Helicobacter pylori. Here, we report …

A new series of arylmethylene hydrazine derivatives bearing 1, 3-dimethylbarbituric moiety
7a–o were designed, synthesized, and evaluated for their in vitro urease inhibitory activity …

This article describes the design and synthesis of a series of novel amantadine-thiourea
conjugates (3a–j) as Jack bean urease inhibitors. The synthesized hybrids were assayed for …

Urease is known to be one of the major causes of diseases induced by Helicobacter pylori,
thus allow them to survive at low pH inside the stomach and thereby, play an important role …

Urease is known as a virulence factor of some pathogen in the living organism. In this study,
a novel series of phenylurea conjugated to different alkyl pyridinium were designed …

Abstract A series of 1-[(4′-chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives 1–
25 was synthesized and characterized by spectroscopic techniques such as EI-MS and 1 H …

A series of 2, 5-substituted-1, 4-benzoquinone (1–6) were prepared and structurally
characterized by elemental analysis, IR spectra, 1H and 13C NMR spectra, and single …