Early life adversity is consequential for poor cognitive health in mid to late-life. Early life
adversity is associated with higher allostatic load, a biological indicator of physiological …

Background Allostatic load (AL) indicates the cumulative impact of stress on homeostatic
mechanisms. Depression and AL have been associated with cognitive deficits, but it is …

Allostatic load (AL) has been proposed as a general framework for understanding the
cumulative effects of life stress on individuals. Despite growing interest in AL, limited …

Multiple biological processes are related to cognitive impairment in older adults, but their
combined impact on cognition in midlife is not known. Using an array of measurements …

Previous research suggests that high allostatic load (AL), a biological indicator of
physiological dysregulation due to chronic stress, is associated with poor cognitive …

The allostatic load model expands the stress-disease literature by proposing a temporal
cascade of multi-systemic physiological dysregulations that contribute to disease …

We investigated whether cognitive fitness in late midlife is associated with physiological and
psychological factors linked to increased risk of age-related cognitive decline. Eighty-one …

We examined the effects of early life stress on cognitive ability and decline among men of
the Helsinki Birth Cohort Study, 10% of whom were separated temporarily (mean age at …

Allostatic load (AL) has been proposed as a new conceptualization of cumulative biological
burden exacted on the body through attempts to adapt to life's demands. Using a …

Early-life stress (ELS) has previously been identified as a risk factor for cognitive decline, but
this work has predominantly focused on clinical groups and indexed traditional cognitive …