A high‐fat diet has a tissue‐specific effect on adiponectin and related enzyme expression

M Barnea, A Shamay, AH Stark, Z Madar - Obesity, 2006 - Wiley Online Library
Objective: This study was designed to test whether adiponectin plays a role in diet‐induced
obesity and insulin resistance and acts as a mediator to induce or inhibit specific metabolic …

Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice

JW Bullen Jr, S Bluher, T Kelesidis… - American Journal of …, 2007 - journals.physiology.org
Adiponectin and its receptors play an important role in energy homeostasis and insulin
resistance, but their regulation remains to be fully elucidated. We hypothesized that high-fat …

Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet

S Otabe, X Yuan, T Fukutani, N Wada… - American Journal …, 2007 - journals.physiology.org
Adiponectin, a physiologically active polypeptide secreted by adipocytes, shows insulin-
sensitizing, anti-inflammatory, and antiatherogenic properties in rodents and humans. To …

Caloric restriction increases adiponectin expression by adipose tissue and prevents the inhibitory effect of insulin on circulating adiponectin in rats

Q Ding, C Ash, T Mracek, B Merry, C Bing - The Journal of nutritional …, 2012 - Elsevier
Aging is associated with redistribution of body fat and the development of insulin resistance.
White adipose tissue emerges as an important organ in controlling life span. Caloric …

Fat depot-specific expression of adiponectin is impaired in Zucker fatty rats

J Altomonte, S Harbaran, A Richter, H Dong - Metabolism, 2003 - Elsevier
Adiposity, particularly increased intra-abdominal fat, is a predisposing factor for the
development of insulin resistance in obesity and type 2 diabetes. Visceral fat seems to differ …

A fat-enriched, glucose-enriched diet markedly attenuates adiponectin mRNA levels in rat epididymal adipose tissue

EK Naderali, D Estadella, M Rocha… - Clinical …, 2003 - portlandpress.com
Adiponectin levels are decreased in subjects with obesity, diabetes and coronary artery
disease. In the present study, we have investigated whether the decrease in the levels and …

Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in …

K Hotta, T Funahashi, NL Bodkin, HK Ortmeyer… - Diabetes, 2001 - Am Diabetes Assoc
Adiponectin is an adipose-specific plasma protein whose plasma concentrations are
decreased in obese subjects and type 2 diabetic patients. This protein possesses putative …

Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-α expression

PA Kern, GB Di Gregorio, T Lu, N Rassouli… - Diabetes, 2003 - Am Diabetes Assoc
Adiponectin is a 29-kDa adipocyte protein that has been linked to the insulin resistance of
obesity and lipodystrophy. To better understand the regulation of adiponectin expression …

Energy intake and adiponectin gene expression

L Qiao, B Lee, B Kinney, H Yoo… - American Journal of …, 2011 - journals.physiology.org
Hypoadiponectinemia and decreased adiponectin gene expression in white adipose tissue
(WAT) have been well observed in obese subjects and animal models. However, the …

The postprandial response of adiponectin to a high-fat meal in normal and insulin-resistant subjects

PW Peake, AD Kriketos, GS Denyer… - International journal of …, 2003 - nature.com
OBJECTIVE: Adiponectin is an adipose-specific protein with short-term effects in vivo on
glucose and fatty acid levels. We studied the plasma concentration and the proteolytic …