Alterations in plasma lipoproteins are major risk factors for coronary heart disease caused
by atherosclerosis. The purpose of this chapter is to provide the reader with an overview of …

It is well recognized that the lowering of low-density lipoprotein (LDL) cholesterol can
substantially reduce coronary artery disease (CAD)–related morbidity and mortality. The …

Over 200 risk factors for cardiovascular disease (CVD) have now been identified. Among
these, the three most important are (1) abnormal lipids, including the fact that there are more …

A substantial body of evidence suggests that circulating levels of high-density lipoprotein
(HDL) and certain triglyceride-carrying lipoproteins may, like low-density lipoprotein (LDL) …

In many patients with coronary artery disease, a low level of high‐density lipoprotein
cholesterol (HDL‐C), rather than substantially elevated lowdensity lipoprotein cholesterol …

Low levels of high-density lipoprotein (HDL) cholesterol are associated with an increased
risk of coronary artery disease events. Data in animals indicate that increasing HDL …

Attention has recently been focused on the association between plasma high density
lipoprotein (HDL) concentration and the risk of coronary heart disease (CHD)(1–6). Unlike …

Clinical data show that a 1% increase in serum concentrations of high-density lipoprotein
cholesterol (HDL-C) can decrease cardiovascular risk by 2% to 3%. Therefore, mechanisms …

Atherogenic dyslipidemia is a lipoprotein profile combining 4 specific abnormalities:
borderline-high total cholesterol levels; high triglyceride concentrations; small, dense, low …

The lipid-atherogenesis connection has undergone an evolutionary metamorphosis from a
focus initially on serum total cholesterol, subsequently on other lipids, then on the …