Objective High levels of both angiotensin (Ang) II and tumor necrosis factor (TNF)-α have
been implicated in the pathogenesis of glomerular injury by affecting podocytes. The aim of …

Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the
kidney. Background Emerging evidence suggests that angiotensin II (Ang II) is not only a …

Infusion of angiotensin II reduces loss of glomerular capillary area in the early phase of anti-
Thy-1.1 nephritis possibly via regulating angiogenesis-associated factors. Background …

In the present study, we tested the hypothesis that the renoprotective effect of an angiotensin
receptor blocker depends on the angiotensin II type 1 (AT1) receptor on podocytes. For this …

Angiotensinogen (AGT) expression in renal proximal tubular cells (RPTCs) and intrarenal
tumor necrosis factor-α (TNF-α) levels are increased in hypertension and renal diseases …

We have previously documented that human mesangial cell (HMC)-derived TNF-α is an
important mediator involved in the glomerulo-tubular communication in the development of …

The aim of this work was to study the role of local intrarenal angiotensin II (Ang II) and the
oxidative stress in the up‐regulation of pro‐inflammatory cytokines expression observed in …

Angiotensin II (ANG II) and nitric oxide (NO) have contrasting vascular effects, yet both
sustain inflammatory responses. We investigated the impact of ANG II on lipopolysaccharide …

Intrarenal angiotensin II is increased in kidney diseases independently of plasma
angiotensin II and is thought to promote progressive deterioration of renal architecture. Here …

The role of the circulating renin–angiotensin system (RAS) in regulating systemic blood
pressure and sodium balance is well established. More recently, researchers have turned …