Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol

P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

Rapid changes in cannabinoid 1 receptor availability in cannabis-dependent male subjects after abstinence from cannabis

DC D'Souza, JA Cortes-Briones… - Biological psychiatry …, 2016 - Elsevier
Background The widespread use of cannabis, the increasing legalization of “medical”
cannabis, the increasing potency of cannabis, and the growing recreational use of synthetic …

Does cannabis composition matter? Differential effects of delta-9-tetrahydrocannabinol and cannabidiol on human cognition

M Colizzi, S Bhattacharyya - Current Addiction Reports, 2017 - Springer
Abstract Purpose of Review The lack of clarity about the effect of cannabis use on cognition
may be attributable to the considerable heterogeneity among studies in terms of cannabis …

Cannabis and psychiatric disorders: it is not only addiction

FM Leweke, D Koethe - Addiction biology, 2008 - Wiley Online Library
Since the discovery of the endocannabinoid system, a growing body of psychiatric research
has emerged focusing on the role of this system in major psychiatric disorders like …

Basic neuroanatomy and neuropharmacology of cannabinoids

CS Breivogel, LJ Sim-Selley - International Review of Psychiatry, 2009 - Taylor & Francis
Humans have used Cannabis sativa (marijuana) for at least 12,000 years, but researchers
have only recently described an endogenous cannabinoid system. The endocannabinoid …

Cannabis: a treasure trove or pandora's box?

K Solymosi, A Köfalvi - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …

Cannabis induced dopamine release: an in-vivo SPECT study

LNP Voruganti, P Slomka, P Zabel, A Mattar… - Psychiatry Research …, 2001 - Elsevier
In a research study aimed at examining the alterations in dopaminergic function in
schizophrenia, the authors identified a surreptitious case scenario which provided new …

The association between regular cannabis exposure and alterations of human brain morphology: an updated review of the literature

V Lorenzetti, N Solowij, A Fornito… - Current …, 2014 - ingentaconnect.com
Cannabis is the most widely used illicit drug worldwide, though it is unclear whether its
regular use is associated with persistent alterations in brain morphology. This review …

Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 …

SD Lichenstein, N Manco, LM Cope, L Egbo… - …, 2022 - nature.com
Cannabis use peaks in adolescence, and adolescents may be more vulnerable to the neural
effects of cannabis and cannabis-related harms due to ongoing brain development during …

Cannabis and neurodevelopment: implications for psychiatric disorders

S Sundram - Human Psychopharmacology: Clinical and …, 2006 - Wiley Online Library
The developing brain is susceptible to the effects of exogenous cannabinoids both during
the perinatal period through maternal cannabis use and in young adolescent users …