The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …

Publisher Summary This chapter illustrates the fruitfulness of an integrated theoretical and
empirical approach. The emphasis is on the emergent structural and functional neural …

Failures of neural tube closure are common and serious birth defects, yet we have a poor
understanding of the interaction of genetics and cell biology during neural tube closure …

Neurons begin their life as simple spheres, but can ultimately assume an elaborate
morphology with numerous, highly arborized dendrites, and long axons. This is achieved via …

Background Neurulation is driven by apical constriction of actomyosin cytoskeleton resulting
in conversion of the primitive lumen into the central canal in a mechanism driven by F-actin …

As opposed to the neural crest, the neural epithelium is generally viewed as a static and
cohesive structure. Here, using an ex vivo system free of the environmental influences and …

The development of the neural crest up to the stage where they leave the neural tube can be
observed as a series of concatenated but independent events that involve dorsalization of …

The neural tube formation during gestational development is a complicated morphogenic
process that requires various cell signaling and regulation by a variety of genes. It starts …

The neural tube in amniotic embryos forms as a result of two consecutive events along the
anteroposterior axis, referred to as primary and secondary neurulation (PN and SN). While …

To examine the role of actin microfilaments in mouse spinal neurulation, we stained
cryosections of E8. 5‐10.5 CBA/Ca embryos with FITC‐phalloidin. Microfilaments are …