Bile acids (BAs) are the major metabolic product of cholesterol, having detergent-like
activities and being responsible for absorption of lipid and lipid-soluble vitamins. In addition …

Chronic cholestatic liver diseases, such as primary biliary cholangitis (PBC) and primary
sclerosing cholangitis (PSC), are associated with bile stasis and gradually progress to …

Bile acids (BAs) function as detergents promoting nutrient absorption and as hormones
regulating nutrient metabolism. Most BAs are key regulatory factors of physiological …

Bile acids (BAs) are originally known as detergents essential for the digestion and
absorption of lipids. In recent years, extensive research has unveiled new functions of BAs …

Bile acids (BAs) can regulate their own metabolism and transport as well as other key
aspects of metabolic homeostasis via dedicated (nuclear and G protein-coupled) receptors …

Liver diseases and related complications have become one of the leading causes of
morbidity and mortality worldwide, yet effective medicine or approved treatment approach is …

Highlights•Cholestatic liver diseases and bile acid homeostasis are closely
connected.•Numerous signaling molecules are associated with bile acid transporters, tight …

Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

Bile acids (BAs), key regulators in the metabolic network, are not only involved in lipid
digestion and absorption but also serve as potential therapeutic targets for metabolic …

Bile acids (BAs) are not only facilitators participating in the absorption of dietary lipids and
soluble vitamins, but are also important signaling molecules exerting versatile …