Tyrosinase inhibitors from natural and synthetic sources as skin-lightening agents

MN Masum, K Yamauchi, T Mitsunaga - Reviews in Agricultural …, 2019 - jstage.jst.go.jp
Melanin, a major pigment in mammalian skin, is known to protect the skin against harmful
effects of ultraviolet (UV) irradiation, oxidative stress, and DNA damage. The accumulation …

Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries

S Parvez, M Kang, HS Chung… - … Research: An International …, 2007 - Wiley Online Library
Tyrosinase is a copper‐containing enzyme, which is widely distributed in microorganisms,
animals and plants and is a key enzyme in melanin biosynthesis, involved in determining …

Natural, semisynthetic and synthetic tyrosinase inhibitors

SY Lee, N Baek, T Nam - Journal of Enzyme Inhibition and …, 2016 - Taylor & Francis
Tyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing
tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet …

An updated review of tyrosinase inhibitors

TS Chang - International journal of molecular sciences, 2009 - mdpi.com
Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which
catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic …

Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future

YJ Kim, H Uyama - Cellular and molecular life sciences CMLS, 2005 - Springer
Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining
the color of mammalian skin and hair. Various dermatological disorders, such as melasma …

Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: A systematic review

RJ Obaid, EU Mughal, N Naeem, A Sadiq… - RSC …, 2021 - pubs.rsc.org
Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

A comprehensive review on tyrosinase inhibitors

S Zolghadri, A Bahrami, MT Hassan Khan… - Journal of enzyme …, 2019 - Taylor & Francis
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Recent discovery of tyrosinase inhibitors in traditional Chinese medicines and screening methods

J Li, C Li, X Peng, S Li, B Liu, C Chu - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Tyrosinase, the key rate-limiting enzyme for
melanogenesis, is one of the main targets for skin senescence and some pigmented skin …

Advances in the tyrosinase inhibitors from plant source

M Bonesi, J Xiao, R Tundis, F Aiello… - Current medicinal …, 2019 - ingentaconnect.com
Tyrosinase is a multifunctional copper-containing oxidase which catalyses the oxidation of
tyrosine to produce melanin. The alteration in melanin biosynthesis occurs in many …

An updated organic classification of tyrosinase inhibitors on melanin biosynthesis

CY Chen, LC Lin, WF Yang, J Bordon… - Current Organic …, 2015 - ingentaconnect.com
Tyrosinase (EC 1.14. 18.1) is known to be the rate-limiting enzyme responsible for
catalyzing the first two steps in the synthesis of melanin pigments that determine the coloring …