Transgenic research usually involves a large investment in carrying out a series of low-
efficiency steps to produce a few transgenic founder animals, and then characterizing a …

The introduction of specific genes into the genome of farm animals and its stable
incorporation into the germ line has been a major technological advance in agriculture …

The notion of directly introducing new genes or otherwise directly manipulating the genotype
of an animal is conceptually straightforward and appealing because of the speed and …

Transgenic livestock came into existence in 1985 with the production of the first transgenic
pigs and sheep (Hammer et al., 1985). Since then, various technologies have been …

Hundreds of millions of dollars were invested in transgenic farm-animal research between
1983 and 1997, much of it by the private sector, primarily for producing pharmaceutical …

The notion of directly introducing new genes or otherwise manipulating the genotype of an
animal is conceptually straightforward and appealing from the standpoints of both speed …

There are numerous tools available to modify the genetic makeup of animals. They are
being used to good advantage for studying basic biological phenomena. Within the decade …

Agriculture is a multibillion dollar industry in the United States alone [1]. It is no wonder that
livestock species have been considered obvious candidates for genetic engineering. When …

Techniques have been developed to introduce specific genes from one species into the
germplasm of another, including livestock. This paper reviews reports on evaluation …

In our continuing quest to improve the efficiency of producing transgenic animals, we have
compared the influence of two transgene purification techniques on the efficiency of creating …