Curcumin―the paradigm of a multi-target natural compound with applications in cancer prevention and treatment

MH Teiten, S Eifes, M Dicato, M Diederich - Toxins, 2010 - mdpi.com
As cancer is a multifactor disease, it may require treatment with compounds able to target
multiple intracellular components. We summarize here how curcumin is able to modulate …

Biological and therapeutic activities, and anticancer properties of curcumin

D Perrone, F Ardito… - Experimental and …, 2015 - spandidos-publications.com
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant.
Curcumin has been used extensively in Ayurvedic medicine, as it is nontoxic and exhibits a …

Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent

M López‐Lázaro - Molecular nutrition & food research, 2008 - Wiley Online Library
A growing body of research suggests that curcumin, the major active constituent of the
dietary spice turmeric, has potential for the prevention and therapy of cancer. Preclinical …

The role of curcumin in prevention and management of metastatic disease

BE Bachmeier, PH Killian, D Melchart - International journal of molecular …, 2018 - mdpi.com
In the last two decades, targeted therapies have enhanced tumor patient care and treatment
success, however, metastatic growth still cannot be stopped efficiently and, therefore …

[PDF][PDF] The effect of curcumin on breast cancer cells

D Liu, Z Chen - Journal of breast cancer, 2013 - synapse.koreamed.org
Curcumin, which is extracted from the plant Curcuma longa, has been used in the
therapeutic arsenal for clinical oncology. Curcumin has chemopreventive and antitumoral …

Farmer to pharmacist: curcumin as an anti-invasive and antimetastatic agent for the treatment of cancer

D Bandyopadhyay - Frontiers in chemistry, 2014 - frontiersin.org
A huge number of compounds are widely distributed in nature and many of these possess
medicinal/biological/pharmacological activity. Curcumin, a polyphenol derived from the …

Targeting cancer stem cells by curcumin and clinical applications

Y Li, T Zhang - Cancer letters, 2014 - Elsevier
Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an
Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and …

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

R Wilken, MS Veena, MB Wang, ES Srivatsan - Molecular cancer, 2011 - Springer
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant,
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …

Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways

AH Rahmani, MA Al Zohairy, SM Aly… - BioMed research …, 2014 - Wiley Online Library
Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact
cause of cancer development and progression is not fully known. But it is thought that cancer …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …