Risk-based chemical safety assessments are increasingly being conducted to support
chemical management decisions and informed substitution to protect public health. Rapid …

To effectively incorporate in vitro-in silico-based methods into the regulation of consumer
product safety, a quantitative connection between product phthalate concentrations and in …

The US Environmental Protection Agency (EPA) is currently conducting separate Toxic
Substances Control Act (TSCA) risk evaluations for seven phthalates: dibutyl phthalate …

Abstract The Maximum Cumulative Ratio (MCR) quantifies the degree to which a single
chemical drives the cumulative risk of an individual exposed to multiple chemicals …

Abstract Background The EU 6th Framework Program (FP)-funded Health and Environment
Network (HENVINET) aimed to support informed policy making by facilitating the availability …

Some phthalates such as di (2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP)
and their metabolites are suspected of producing teratogenic or endocrine-disrupting effects …

The constantly evolving science of risk assessment is currently faced with many challenges,
not only from the interpretation of the volume of data being generated with new innovative …

As a result of concerns about the toxicity of phthalates to humans, several expert panels
were convened toward the end of the 1990s to evaluate the implications of the scientific …

The probability of nonoccupational exposure to phthalates is high given their use in a vast
range of consumables, including personal care products (eg, perfumes, lotions, cosmetics) …

A few different exposure prediction tools were evaluated for use in the new in vitro-based
safety assessment paradigm using di-2-ethylhexyl phthalate (DEHP) and dibutyl phthalate …