Evaluating cannabis use risk reduction as an alternative clinical outcome for cannabis use disorder.

BJ Sherman, MJ Sofis, JT Borodovsky… - … of addictive behaviors, 2022 - psycnet.apa.org
Objective: Abstinence is rarely achieved in clinical trials for cannabis use disorder (CUD).
Cannabis reduction is associated with functional improvement, but reduction endpoints have …

Characterizing cannabis use reduction and change in functioning during treatment: Initial steps on the path to new clinical endpoints.

JT Borodovsky, MJ Sofis, BJ Sherman… - … of addictive behaviors, 2022 - psycnet.apa.org
Reduction-based cannabis use endpoints are needed to better evaluate treatments for
cannabis use disorder (CUD). This exploratory, secondary analysis aimed to characterize …

Treatment of cannabis use disorder: current science and future outlook

BJ Sherman, AL McRae‐Clark - Pharmacotherapy: The Journal …, 2016 - Wiley Online Library
Cannabis is the most commonly used illicit substance in the United States. Rates of
cannabis use and cannabis use disorder (CUD) have increased in the past decade …

Primary outcomes in two randomized controlled trials of treatments for cannabis use disorders

EN Peters, C Nich, KM Carroll - Drug and Alcohol Dependence, 2011 - Elsevier
BACKGROUND: While several randomized controlled trials evaluating a range of treatments
for cannabis use disorders have appeared in recent years, these have been marked by …

Non-abstinent treatment outcomes for cannabis use disorder

FR Levin, JJ Mariani, CJ Choi, C Basaraba… - Drug and alcohol …, 2021 - Elsevier
Background Abstinence remains a standard outcome for potential treatment interventions for
Cannabis Use Disorder (CUD). However, there needs to be validation of non-abstinent …

Measuring within-individual cannabis reduction in clinical trials: a review of the methodological challenges

RL Tomko, KM Gray, MA Huestis, LM Squeglia… - Current addiction …, 2019 - Springer
Abstract Purpose of Review Cannabis abstinence, traditionally, is the primary outcome in
cannabis use disorder (CUD) treatment trials. Due to the changing legality of cannabis …

Systematic review of outcome domains and measures used in psychosocial and pharmacological treatment trials for cannabis use disorder

DC Lee, NJ Schlienz, EN Peters, RH Dworkin… - Drug and alcohol …, 2019 - Elsevier
Cannabis use disorder (CUD) is prevalent and demand for treatment is increasing, yet few
individuals engage in formal treatment and the efficacy of established interventions for CUD …

Cessation of cannabis use: A retrospective cohort study

AK Seidel, A Pedersen, R Hanewinkel… - Psychiatry …, 2019 - Elsevier
Given recent findings of a worldwide increase in cannabis use, a better understanding of the
factors associated with cannabis use is needed. Most previous studies have focused on …

Psychosocial and pharmacological interventions for the treatment of cannabis use disorder

P Sabioni, B Le Foll - FOCUS, A Journal of the American …, 2019 - Am Psychiatric Assoc
Cannabis use has been continuously increasing, and cannabis use disorder (CUD) has
become a public health issue. Some psychosocial interventions have demonstrated the …

Tobacco use during cannabis cessation: Use patterns and impact on abstinence in a National Drug Abuse Treatment Clinical Trials Network study

EA McClure, NL Baker, SC Sonne, UE Ghitza… - Drug and alcohol …, 2018 - Elsevier
Background It is common for cannabis users to also use tobacco. While data suggest that
tobacco users have more difficulty achieving cannabis cessation, secondary analyses of …