Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans
DA Martins, N Mazibuko, F Zelaya… - Nature …, 2020 - nature.com
Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …
physiology when delivered intranasally? We address this question by contrasting two …
Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research
DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …
behavior have steadily increased over the last two decades, stimulating considerable …
Oxytocin's effect on resting-state functional connectivity varies by age and sex
The neuropeptide oxytocin plays a role in social cognition and affective processing. The
neural processes underlying these effects are not well understood. Modulation of …
neural processes underlying these effects are not well understood. Modulation of …
Intranasal oxytocin administration dampens amygdala reactivity towards emotional faces in male and female PTSD patients
Post-traumatic stress disorder (PTSD) is a disabling psychiatric disorder. As a substantial
part of PTSD patients responds poorly to currently available psychotherapies …
part of PTSD patients responds poorly to currently available psychotherapies …
Intranasal oxytocin normalizes amygdala functional connectivity in posttraumatic stress disorder
The neuropeptide oxytocin (OT) has been suggested as a promising pharmacological agent
for medication-enhanced psychotherapy in posttraumatic stress disorder (PTSD) because of …
for medication-enhanced psychotherapy in posttraumatic stress disorder (PTSD) because of …
Oxytocin attenuates amygdala responses to emotional faces regardless of valence
BACKGROUND: Oxytocin is known to reduce anxiety and stress in social interactions as
well as to modulate approach behavior. Recent studies suggest that the amygdala might be …
well as to modulate approach behavior. Recent studies suggest that the amygdala might be …
[HTML][HTML] A spatiotemporal profile of in vivo cerebral blood flow changes following intranasal oxytocin in humans
Background Animal and human studies highlight the role of oxytocin in social cognition and
behavior and the potential of intranasal oxytocin (IN-OT) to treat social impairment in …
behavior and the potential of intranasal oxytocin (IN-OT) to treat social impairment in …
Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay
MR Lee, KB Scheidweiler, XX Diao, F Akhlaghi… - Molecular …, 2018 - nature.com
Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …
Inverse effects of oxytocin on attributing mental activity to others in depressed and healthy subjects: a double-blind placebo controlled FMRI study
D Pincus, S Kose, A Arana, K Johnson… - Frontiers in …, 2010 - frontiersin.org
Background: Oxytocin is a stress-attenuating and pro-social neuropeptide. To date, no study
has looked at the effects of oxytocin in modulating brain activity in depressed individuals nor …
has looked at the effects of oxytocin in modulating brain activity in depressed individuals nor …
Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques
ME Modi, F Connor-Stroud, R Landgraf… - …, 2014 - Elsevier
Intranasal (IN) administration is a widely used method for examining the effect of oxytocin
(OT) on social behavior and cognition in healthy subjects and psychiatric populations. IN-OT …
(OT) on social behavior and cognition in healthy subjects and psychiatric populations. IN-OT …