Oxytocin increases amygdala reactivity to threatening scenes in females

A Lischke, M Gamer, C Berger, A Grossmann… - …, 2012 - Elsevier
The neuropeptide oxytocin (OT) is well known for its profound effects on social behavior,
which appear to be mediated by an OT-dependent modulation of amygdala activity in the …

Intranasal oxytocin selectively attenuates rhesus monkeys' attention to negative facial expressions

LA Parr, M Modi, E Siebert, LJ Young - Psychoneuroendocrinology, 2013 - Elsevier
Intranasal oxytocin (IN-OT) modulates social perception and cognition in humans and could
be an effective pharmacotherapy for treating social impairments associated with …

Improving the precision of intranasal oxytocin research

A Winterton, LT Westlye, NE Steen… - Nature Human …, 2021 - nature.com
The neuropeptide oxytocin has been popularized for its role in social behaviour and
nominated as a candidate treatment for several psychiatric illnesses due to promising …

Sex, receptors, and attachment: a review of individual factors influencing response to oxytocin

KS MacDonald - Frontiers in neuroscience, 2013 - frontiersin.org
As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal
oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry …

Oxytocin and the social brain: neural mechanisms and perspectives in human research

M Kanat, M Heinrichs, G Domes - Brain research, 2014 - Elsevier
The present paper summarizes functional imaging studies investigating the effects of
intranasal oxytocin (OT) on brain responses to social stimuli. We aim to integrate previous …

Sex-dependent neural effect of oxytocin during subliminal processing of negative emotion faces

L Luo, B Becker, Y Geng, Z Zhao, S Gao, W Zhao… - Neuroimage, 2017 - Elsevier
In line with animal models indicating sexually dimorphic effects of oxytocin (OXT) on social-
emotional processing, a growing number of OXT-administration studies in humans have …

Oxytocin's neurochemical effects in the medial prefrontal cortex underlie recovery of task-specific brain activity in autism: a randomized controlled trial

Y Aoki, T Watanabe, O Abe, H Kuwabara… - Molecular …, 2015 - nature.com
The neuropeptide oxytocin may be an effective therapeutic strategy for the currently
untreatable social and communication deficits associated with autism. Our recent paper …

Elevated cerebrospinal fluid and blood concentrations of oxytocin following its intranasal administration in humans

N Striepens, KM Kendrick, V Hanking, R Landgraf… - Scientific reports, 2013 - nature.com
There has been an unprecedented interest in the modulatory effects of intranasal oxytocin
on human social cognition and behaviour, however as yet no study has actually …

The effect of intranasal administration of oxytocin on fear recognition

M Fischer-Shofty, SG Shamay-Tsoory, H Harari… - Neuropsychologia, 2010 - Elsevier
The oxytocinergic system has recently been placed amongst the most promising targets for
various psychiatric treatments due to its role in prosocial behavior and anxiety reduction …

Statistical and methodological considerations for the interpretation of intranasal oxytocin studies

H Walum, ID Waldman, LJ Young - Biological psychiatry, 2016 - Elsevier
Over the last decade, oxytocin (OT) has received focus in numerous studies associating
intranasal administration of this peptide with various aspects of human social behavior …