An association between EGF and EGFR gene polymorphisms with gastric cancer in a Chinese Han population.

G Yang, L Rao, L Tian, X Cai - Hepato-gastroenterology, 2012 - europepmc.org
Results The A allele of EGF+ 61 G/A was less frequently in gastric cancer patients than in
controls (OR= 0.73, 95% CI= 0.55-0.95, p= 0.02). The A allele frequency was also …

No Association Between EGF Gene Polymorphism and Gastric Cancer

Y Goto, T Ando, H Goto, N Hamajima - Cancer Epidemiology Biomarkers & …, 2005 - AACR
The etiology of gastric cancer is not well-understood. Epidermal growth factor (EGF)
transduces growth signals to mitogen-activated protein kinase via RAS and BRAF, and …

A Single Nucleotide Polymorphism in the 5′ Untranslated Region of the EGF Gene Is Associated with Occurrence and Malignant Progression of Gastric Cancer

Y Hamai, S Matsumura, K Matsusaki, Y Kitadai… - Pathobiology, 2005 - karger.com
Objective: Epidermal growth factor (EGF) has many biological functions and plays an
important role in the progression of various tumors including gastric cancer. An AG single …

Analyses of EGF A61G gene variation and serum EGF level on gastric cancer susceptibility and clinicopathological parameters

C Cacina, S Arikan, Y Düzköylü, MB Doğan… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Epidermal growth factor (EGF) induces various biological signaling pathways,
including proliferation and differentiation and it is the natural ligand of the epidermal growth …

Association between EGF+ 61 A> G polymorphism and gastric cancer risk: a meta-analysis

S Wu, S Jiang, J Wu, G Xiong - Journal of Huazhong University of Science …, 2015 - Springer
Previous studies suggested an association between the EGF+ 61 A> G polymorphism and
susceptibility to gastric cancer, but the results have been inconsistent. To draw a more …

Association between EGF promoter polymorphisms and cancer risk: a meta-analysis

W Xu, Y Li, X Wang, B Chen, S Liu, Y Wang, W Zhao… - Medical Oncology, 2010 - Springer
EGF promoter polymorphisms are observed to modulate EGF levels and thought to have
effect on susceptibility to various carcinomas but the results are inconsistent. In this meta …

[PDF][PDF] Analysis of the polymorphisms EGFR-r521K and ERBB2-I655V in Mexican patients with gastric cancer and premalignant gastric lesions

JH Torres-Jasso, AR Bustos-Carpinteyro, ME Marín… - Rev Invest …, 2013 - academia.edu
The proto-oncogenes epidermal growth factor receptor (EGFR) and erythroblastic leukemia
viral oncogene homolog 2 (ERBB2), are involved in the development of diverse malignant …

[HTML][HTML] Association between EGF+ 61A/G polymorphism and gastric cancer in Caucasians

AP Araújo, BM Costa, AL Pinto-Correia… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To investigate the association between epidermal growth factor (EGF)+ 61A/G
polymorphism and susceptibility to gastric cancer, through a cross-sectional study …

EGF+ 61A> G polymorphism and gastrointestinal cancer risk: a HuGE review and meta-analysis

Y Piao, Z Liu, Z Ding, L Xu, F Guo, Q Sun, X Xie - Gene, 2013 - Elsevier
Emerging evidences from preclinical and clinical studies have shown that epidermal growth
factor (EGF) has some effectiveness against endogenously arising carcinogenesis …

[HTML][HTML] EGF+ 61A/G polymorphism contributes to increased gastric cancer risk: evidence from a meta-analysis

Q Peng, S Li, X Qin, X Lao, Z Chen, X Zhang… - Cancer Cell …, 2014 - Springer
Background Epidermal growth factor (EGF) plays a pivotal role in cell proliferation,
differentiation, and tumorigenesis of epithelial tissues. Variation of the EGF+ 61A/G …