Synthesis and characterization of silica nanoparticles from rice ashes coated with chitosan/cancer cell membrane for hepatocellular cancer treatment

MJC Espinoza, KS Lin, MT Weng, SC Kunene… - International Journal of …, 2023 - Elsevier
Dual pH-sensitive smart nanocarriers based on silica nanoparticles (SNPs) extracted from
rice husk ashes (RHAs) to effectively inhibit liver cancer cell proliferation were investigated …

Chitosan mediated 5-Fluorouracil functionalized silica nanoparticle from rice husk for anticancer activity

D Dhinasekaran, R Raj, AR Rajendran… - International journal of …, 2020 - Elsevier
Herein, we have reported a cost-effective method of synthesizing highly efficient silica
nanomaterial from rice husks for its application as a chemotherapeutic agent. Silica particle …

Preparation and in-vitro evaluation of mesoporous biogenic silica nanoparticles obtained from rice and wheat husk as a biocompatible carrier for anti-cancer drug …

S Porrang, N Rahemi, S Davaran, M Mahdavi… - European Journal of …, 2021 - Elsevier
In this study, mesoporous silica nanocarriers were synthesized from natural sources such as
rice and wheat husk for drug delivery application. First, the biogenic silica in cereals husk …

Hollow chitosan–silica nanospheres for doxorubicin delivery to cancer cells with enhanced antitumor effect in vivo

E Yan, Y Fu, X Wang, Y Ding, H Qian… - Journal of Materials …, 2011 - pubs.rsc.org
Here we report the synthesis of hybrid hollow chitosan–silica nanospheres (CS–Silica NPs)
with chitosan–polyacrylic acid (CS–PAA) nanoparticles as the template and doxorubicin …

Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles as hepatocellular carcinoma-targeted drug carrier

Y Lv, J Li, H Chen, Y Bai, L Zhang - International journal of …, 2017 - Taylor & Francis
In this study, a glycyrrhetinic acid-functionalized mesoporous silica nanoparticle (MSN-GA)
was prepared for active tumor targeting. MSN-GA exhibited satisfactory loading capacity for …

[HTML][HTML] Functionalised mesoporous silica nanoparticles with excellent cytotoxicity against various cancer cells for pH-responsive and controlled drug delivery

SS Park, MH Jung, YS Lee, JH Bae, SH Kim, CS Ha - Materials & design, 2019 - Elsevier
Mesoporous silica nanoparticles (MSNs) modified with Pt and carboxyl groups were
designed and the drug molecule-release behaviour was studied by loading cisplatin as a …

Effect of surface functionality of silica nanoparticles on cellular uptake and cytotoxicity

S Jambhrunkar, Z Qu, A Popat, J Yang… - Molecular …, 2014 - ACS Publications
Mesoporous silica nanoparticles (MCM-41) with different surface chemistry were used as
carrier system to study its influence on drug delivery and anticancer activity of curcumin …

Chitosan‐capped mesoporous silica nanoparticles as pH‐responsive nanocarriers for controlled drug release

X Hu, Y Wang, B Peng - Chemistry–An Asian Journal, 2014 - Wiley Online Library
Herein, we present a straightforward synthesis of pH‐responsive chitosan‐capped
mesoporous silica nanoparticles (MSNs). These MCM‐41‐type MSNs could be used as …

Facile preparation of multifunctional hollow silica nanoparticles and their cancer specific targeting effect

B Sahoo, KSP Devi, SK Sahu, S Nayak, TK Maiti… - Biomaterials …, 2013 - pubs.rsc.org
Efficient delivery of therapeutics to tumor cells is one of the key issues in cancer therapy. In
the present work, we have established a facile and unique chemical strategy for fabrication …

A chitosan/mesoporous silica nanoparticle-based anticancer drug delivery system with a “tumor-triggered targeting” property

T Liao, C Liu, J Ren, H Chen, Y Kuang, B Jiang… - International Journal of …, 2021 - Elsevier
To enhance drug utilization and reduce their side effects, the strategy of “tumor-triggered
targeting” was introduced to fabricate dual-pH-sensitive chitosan (CHI)/mesoporous silica …