“Life's Essential 8” cardiovascular health and dementia risk, cognition, and neuroimaging markers of brain health

R Zhou, HW Chen, FR Li, Q Zhong, YN Huang… - Journal of the American …, 2023 - Elsevier
Objective To evaluate associations of Life's Essential 8 (LE8) score, the recently updated
metric for promoting cardiovascular health (CVH), with the risk of incident dementia and its …

[HTML][HTML] Association between the AHA Life's Essential 8 score and incident all-cause dementia: a prospective cohort study from UK Biobank

F Petermann-Rocha, S Deo, D Lyall, AR Orkaby… - Current Problems in …, 2023 - Elsevier
This study aimed to investigate the association between the Life's Essential 8 (LE8) score
and incident all-cause dementia (including Alzheimer's disease [AD] and vascular dementia) …

Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype

J Guo, AM Brickman, JJ Manly, C Reitz… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction There is limited and inconsistent reporting on the association between Life's
Simple 7 (LS7) and dementia in the elderly population. Methods Based on the Washington …

Optimal cardiovascular health is associated with slower cognitive decline

NV Ferreira, NG Gonçalves, C Szlejf… - European Journal of …, 2024 - Wiley Online Library
Abstract Background Life's Simple 7, a lifestyle and cardiovascular index associated with
cognition, has been updated to Life's Essential 8 (LE8) to include sleep. LE8 has been …

Analysis of clinical traits associated with cardiovascular health, genomic profiles, and neuroimaging markers of brain health in adults without stroke or dementia

JN Acosta, CP Both, C Rivier, N Szejko… - JAMA Network …, 2022 - jamanetwork.com
Importance The American Heart Association (AHA) Life's Simple 7 (LS7) score captures 7
biological and lifestyle factors associated with promoting cardiovascular health. Objectives …

Life's Simple 7's cardiovascular health metrics are associated with Hispanic/Latino neurocognitive function: HCHS/SOL results

HM González, W Tarraf, N Gouskova… - Journal of …, 2016 - content.iospress.com
Background: Hispanics/Latinos are purportedly at increased risk for neurocognitive decline
and dementias. Without dementia cures, low-cost, well-tolerated public health means for …

Ideal cardiovascular health and biomarkers of subclinical brain aging: the Northern Manhattan Study

H Gardener, M Caunca, C Dong… - Journal of the …, 2018 - Am Heart Assoc
Background The American Heart Association Life's Simple 7 metric defines ideal
cardiovascular health (CVH) on 7 factors: smoking, diet, physical activity, body mass index …

Association of cardiovascular health level in older age with cognitive decline and incident dementia

C Samieri, MC Perier, B Gaye, C Proust-Lima… - Jama, 2018 - jamanetwork.com
Importance Evidence is limited regarding the relation between cardiovascular health level
and dementia risk. Objective To investigate the association between cardiovascular health …

Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention

I Juul Rasmussen, KL Rasmussen… - European Heart …, 2020 - academic.oup.com
Aims Dementia is a major global challenge for health and social care in aging populations.
A third of all dementia may be preventable due to cardiovascular risk factors. Intensive multi …

Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study

GM Peloso, AS Beiser, CL Satizabal, V Xanthakis… - Neurology, 2020 - AAN Enterprises
Objective To determine the joint role of ideal cardiovascular health (CVH) and genetic risk
on risk of dementia. Methods We categorized CVH on the basis of the American Heart …