Distribution of Immunoglobulin Deposition in the Progressive Multiple Sclerosis Spinal Cord (P7-6.004)

A Lockhart, A Waldmann, M Pisa, J Pansieri… - Neurology, 2024 - AAN Enterprises
Objective: To describe the distribution of immunoglobulins in the MS spinal cord and
relationship with neuropathological outcomes. Background: Cerebrospinal fluid-specific …

Axonal and oligodendrocyte-localized IgM and IgG deposits in MS lesions

MC Sádaba, J Tzartos, C Paíno… - Journal of …, 2012 - Elsevier
BACKGROUND: Recent findings support the important role of antibodies in multiple
sclerosis (MS) physiopathology. Thus, local IgG synthesis is a hallmark of the disease, and …

Spinal Glioblastoma Mimicking Myelin Oligodendrocyte Glycoprotein Antibody Disease Transverse Myelitis (P13-5.021)

A Breitenbucher, C Welsh, M Robers - 2023 - AAN Enterprises
Objective: To present a case of spinal glioblastoma mimicking myelin oligodendrocyte
glycoprotein antibody disease (MOGAD). Background: Spinal cord lesions have a broad …

Variability of the Response to Immunotherapy Among Sub-groups of Patients With Multiple Sclerosis (4107)

I Diouf, C Malpas, D Horakova, E Havrdova, F Patti… - 2021 - AAN Enterprises
Objective: To assess whether patients' response to disease modifying therapies (DMT) in
multiple sclerosis (MS) varies by disease activity (annualised relapse rate, presence of new …

Evaluation of Risk Factors in Developing Lymphopenia and Hypogammaglobulinemia in Anti-CD20 Treated Multiple Sclerosis Patients (5218)

B Vollmer, T Vollmer, J Corboy, E Alvarez - 2020 - AAN Enterprises
Objective: To evaluate risk factors in developing lymphopenia and hypogammaglobulinemia
in anti-CD20 treated MS patients. Background: Anti-CD20 treatment has been associated …

Progression independent of relapses in multiple sclerosis is associated with spinal cord and brain atrophy (P10-3.011)

K Nakamura, S Husak, R Bermel, J Cohen… - 2023 - AAN Enterprises
Objective: To quantify MRI predictors of disability progression and progression independent
of relapse activity (PIRA) from patients with multiple sclerosis (MS) in an observational …

Molecular-Based Diagnosis of Multiple Sclerosis and Its Progressive Stages (P4. 395)

B Bielekova, P Kosa, C Barbour, M Komori… - 2017 - AAN Enterprises
Objective: To determine on an example of multiple sclerosis (MS) if cerebrospinal fluid (CSF)
signatures of complex neurological diseases allow their reliable differentiation from …

Treatment Patterns Among Newly Diagnosed Patients With Multiple Sclerosis by Race and Ethnicity (S40. 001)

C Geiger, D Sheinson, TM To, D Jones, N Bonine - 2022 - AAN Enterprises
Objective: To describe treatment patterns among newly diagnosed patients with multiple
sclerosis (MS) by race and ethnicity. Background: Current treatment guidelines recommend …

A distinctive IgG-mediated pathogenesis for primary progressive multiple sclerosis?

Y Guo, VA Lennon - Brain, 2023 - academic.oup.com
distinctive IgG-mediated pathogenesis for primary progressive multiple sclerosis? | Brain |
Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search …

Investigations on Myelin Oligodendrocyte Glycoprotein Autoimmunity in Children (4368)

T Armangue, G Olive-Cirera, E Martinez-Hernandez… - 2020 - AAN Enterprises
Objective: To report the spectrum of MOG-Ab-associated syndromes in children Background:
Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) have been mainly associated …