Metastasis is the most frequent cause of death in cancer patients. Epithelial-to-mesenchymal
transition (EMT) is the process in which cells lose epithelial integrity and become motile, a …

Metabolic reprogramming is now well established as one of the hallmarks of cancer. The
renewed interest in this topic has spurred a remarkable advance in our understanding of the …

Simple Summary Tumors exhibit metabolic changes that differentiate them from the normal
tissues from which they derive. These metabolic changes favor tumor growth, are primarily …

Anomalous increase in glycolytic activity defines one of the key metabolic alterations in
cancer cells. A realization of this feature has led to critical advancements in cancer detection …

Metabolic reprogramming confers cancer cells plasticity and viability under harsh conditions.
Such active alterations lead to cell metabolic dependency, which can be exploited as an …

Pituitary adenomas are common, benign brain tumors. Some tumors show aggressive
phenotypes including early recurrence, local invasion and distant metastasis, but the …

In recent years, an increasingly more in depth understanding of tumor metabolism in
tumorigenesis, tumor growth, metastasis, and prognosis has been achieved. The broad …

The primary features of cancer are maintained via intrinsically modified metabolic activity,
which is characterized by enhanced nutrient supply, energy production, and biosynthetic …

The uptake and metabolism of nutrients support fundamental cellular process from
bioenergetics to biomass production and cell fate regulation. While many studies of cell …

Tumor microenvironment is characterized by a consistent reduction in oxygen and blood-
borne nutrients that significantly affects the metabolism of distinct cell subsets. Immune cells …