Microinjections of dopaminergic agents in the nucleus accumbens affect ethanol consumption but not palatability

HJ Kaczmarek, SW Kiefer - Pharmacology Biochemistry and Behavior, 2000 - Elsevier
It was determined whether ethanol palatability in rats could be changed by manipulating the
reinforcement experienced during limited access consumption. During the first 3 days of the …

Effect of dopamine agonists and antagonists on ethanol-reinforced behavior: the involvement of the nucleus accumbens

HH Samson, CW Hodge, GA Tolliver, M Haraguchi - Brain research bulletin, 1993 - Elsevier
Rats initiated to self-administer 10% ethanol (v/v) in an operant situation using the sucrose-
substitution technique received bilateral n. accumbens or caudate nucleus microinjections of …

Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

S Rassnick, L Pulvirenti, GF Koob - Psychopharmacology, 1992 - Springer
The purpose of this study was to assess the role of endogenous dopamine and glutamate
systems within the nucleus accumbens in modulating responses for oral ethanol …

Effect of prior ethanol experience on dopamine overflow in accumbens of AA and ANA rats

M Nurmi, T Ashizawa, JD Sinclair… - European journal of …, 1996 - Elsevier
The purpose of this study was to investigate the effect of repeated ethanol administration on
dopamine overflow in the nucleus accumbens of alcohol-preferring AA (Alko Alcohol) and …

Effects of microinjection of the D2 dopamine antagonist raclopride into the ventral tegmental area on ethanol and sucrose self‐administration

HH Samson, AM Chappell - Alcoholism: Clinical and …, 1999 - Wiley Online Library
From previous microinjection studies, a reciprocal feedback between the nucleus
accumbens and the ventral tegmental area (VTA) has been implicated in the reinforcing …

Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants.

F Weiss, MT Lorang, FE Bloom, GF Koob - Journal of Pharmacology and …, 1993 - ASPET
Dopaminergic neurotransmission in the nucleus accumbens may be an important factor in
ethanol reinforcement and genetically determined ethanol preference. This hypothesis was …

Effects of raclopride in the core of the nucleus accumbens on ethanol seeking and consumption: the use of extinction trials to measure seeking

HH Samson, AM Chappell - Alcoholism: Clinical and …, 2004 - Wiley Online Library
Background: A previous study using a sipper procedure of ethanol self‐administration found
that blockade of the D2 dopamine (DA) receptors in the nucleus accumbens resulted in a …

Dopamine release during ethanol drinking in AA rats

M Nurmi, JD Sinclair, K Kiianmaa - Alcoholism: Clinical and …, 1998 - Wiley Online Library
The dopamine overflow in the nucleus accumbens of rats from the high alcohol drinking AA
line was measured by microdialysis before, during, and after one‐half hour sessions of cued …

The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat

S Rassnick, L Stinus, GF Koob - Brain research, 1993 - Elsevier
Rats readily learn to self-administer ethanol using a procedure where ethanol is introduced
in the presence of a sweetener. After gradual removal of the sweetener, sufficient quantities …

Effects of raclopride in the nucleus accumbens on ethanol seeking and consumption

CL Czachowski, AM Chappell… - Alcoholism: Clinical …, 2001 - Wiley Online Library
Background: Nucleus accumbens dopamine has been shown to play a role in the
processing of behaviorally relevant stimuli and to mediate ethanol‐reinforced responding …