Gastric cancer is a gastrointestinal tumor with high morbidity and mortality rates. Several
factors influence its progression, cell death being an important element. In this review, we …

Cisplatin is a commonly used drug for chemotherapy, however, whether it may be used
synergistically with radiotherapy remains unclear. The present study investigated the …

The success of treatment of cancer patients by radiotherapy largely depends on tumor
radiosensitivity. Several molecular factors that determine the sensitivity of tumor cells to …

The elimination of a tumor cell population by exposure of the tumor to lethal doses of drugs
or radiation is a well-established strategy in cancer therapy. Although better cytotoxic chemo …

Background Tumor cell repopulation after radiotherapy is a major cause for the tumor
radioresistance and recurrence. This study aims to investigate the underlying mechanism of …

In recent decades, chemotherapies targeting apoptosis have emerged and demonstrated
remarkable achievements. However, emerging evidence has shown that chemoresistance is …

Cancer is a leading cause of disease-related mortality worldwide. Drug resistance is one of
the primary reasons for the failure of anticancer therapy. There are a number of underlying …

During the EMBO Programmed Cell Death in Model Organisms meeting that was held in
Israel (February 2012), the topic of compensatory proliferation (CP) took an important place …

The traditional treatments for fibrosarcoma have limited efficacy. Therefore, new therapeutic
strategies and/or new adjuvant drugs still need to be explored. Accumulating evidence …

Radiotherapy is an effective treatment for non-small cell lung cancer (NSCLC). However,
irradiated, dying tumor cells generate potent growth stimulatory signals during radiotherapy …