[HTML][HTML] Crosslinking of dialdehyde heparin: a new strategy for improving the anticoagulant properties of porcine acellular dermal matrix

R Feng, N Dan, Y Chen, W Dan - RSC advances, 2022 - pubs.rsc.org
The anticoagulant properties of valve materials are essential to maintain blood patency after
artificial valve implantation. Porcine acellular dermal matrix (pADM) has low …

Dialdehyde pectin-crosslinked and hirudin-loaded decellularized porcine pericardium with improved matrix stability, enhanced anti-calcification and anticoagulant for …

M Hu, X Peng, Y Zhao, X Yu, C Cheng, X Yu - Biomaterials Science, 2021 - pubs.rsc.org
To conveniently and effectively cure heart valve diseases or defects, combined with
transcatheter valve technology, bioprosthetic heart valves (BHVs) originated from the …

Double crosslinking decellularized bovine pericardium of dialdehyde chondroitin sulfate and zwitterionic copolymer for bioprosthetic heart valves with enhanced …

S Shi, M Hu, X Peng, C Cheng, S Feng… - Journal of Materials …, 2024 - pubs.rsc.org
Due to the increasing aging population and the advancements in transcatheter aortic valve
replacement (TAVR), the use of bioprosthetic heart valves (BHVs) in patients diagnosed with …

In vivo biomechanical assessment of triglycidylamine crosslinked pericardium

MS Sacks, H Hamamoto, JM Connolly, RC Gorman… - Biomaterials, 2007 - Elsevier
While glutaraldehyde crosslinking is most often used to fabricate bioprosthetic heart valves
(BHV) using heterograft tissues, it predisposes BHV to calcification and dramatically stiffens …

Hybrid Pericardium with VEGF‐Loaded Hyaluronic Acid Hydrogel Coating to Improve the Biological Properties of Bioprosthetic Heart Valves

Y Lei, L Deng, Y Tang, Q Ning, X Lan… - Macromolecular …, 2019 - Wiley Online Library
Bioprosthetic heart valves (BHVs) used in the clinic are mostly fixed by glutaraldehyde and
the lack of endothelialization is a major problem for glutaraldehyde‐fixed pericardia …

Inorganic‐polymerization crosslinked tissue‐siloxane hybrid as potential biomaterial for bioprosthetic heart valves

F Yang, H He, L Xu, L Jin, G Guo… - Journal of Biomedical …, 2021 - Wiley Online Library
Bioprosthetic heart valve (BHV) replacement is increasingly used for treating valve‐related
diseases worldwide but the current commercially used BHVs treated with glutaraldehyde …

Crosslinking of decellularized porcine heart valve matrix by procyanidins

W Zhai, J Chang, K Lin, J Wang, Q Zhao, X Sun - Biomaterials, 2006 - Elsevier
Heart valve diseases have a significant high mortality, and the valve replacement using
glutaraldehyde crosslinked porcine heart valves is one of the main curing techniques. But its …

Exogenous hyaluronic acid and chondroitin sulfate crosslinking treatment for increasing the amount and stability of glycosaminoglycans in bioprosthetic heart valves

Y Lei, Q Ning, Y Tang, Y Wang - Journal of Materials Science: Materials in …, 2019 - Springer
Glutaraldehyde (GLUT) crosslinked bioprosthetic heart valves (BHVs) might fail due to
progressive degradation and calcification. GLUT cannot stabilize glycosaminoglycans …

Nonglutaraldehyde treated porcine pericardium with good biocompatibility, reduced calcification and improved Anti-coagulation for bioprosthetic heart valve …

T Yu, X Chen, W Zhuang, Y Tian, Z Liang… - Chemical Engineering …, 2021 - Elsevier
Heart valve diseases, such as valve stenosis and regurgitation, are one of the important
reasons for the high morbidity and mortality of cardiovascular diseases, and the heart valve …

Postfunctionalization of biological valve leaflets with a polyphenol network and anticoagulant recombinant humanized type III collagen for improved anticoagulation …

H Wu, K Huang, M Hu, N Chen, Y Qin… - Journal of Materials …, 2023 - pubs.rsc.org
Almost all commercial bioprosthetic heart valves (BHVs) are crosslinked with glutaraldehyde
(GLUT); however, issues such as immune responses, calcification, delayed …