Calcification is a frequent cause of the clinical failure of bioprosthetic heart valves fabricated
from glutaraldehyde pretreated bovine pericardium (GATBP). An investigation was made of …

To address concerns over limitations in the clinical use of glutaraldehyde (GA) fixation in
bioprosthetic heart valves, we manufactured novel, branched poly (ethylene glycol) …

Prosthetic heart valve replacement is an effective therapy for patients with valvular heart
disease. New-type polymer materials provide potential choices of material for preparing …

Bioprosthetic heart valves made from glutaraldehyde (GA)-fixed porcine aortic valves or
bovine pericardium (BP) are having some advantages over mechanical valves. However …

To overcome shortcomings of current heart valve prostheses, novel hybrid valves were
fabricated from decellularized porcine aortic valves coated with poly (3‐hydroxybutyrate‐co …

Valve replacement surgery is the golden standard for end-stage valvular disease due to the
lack of self-repair ability. Currently, bioprosthetic heart valves (BHVs) crosslinked by …

Commercial biological valve leaflets (BVLs) crosslinked with glutaraldehyde (GA) are at risk
of accelerating damage and even failure, owing to the high cell toxicity of GA, acute …

With the coming of an aging society and the emergence of transcatheter valve technology,
the implantation of bioprosthetic heart valves (BHVs) in patients with valvular disease has …

Bovine pericardium (BP) is one of the biological membranes with extensive application in
tissue engineering. To fully investigate the potential clinical applications of this natural …

A novel chemical modification of biological tissues was developed by the direct coupling
heparin to bovine pericardium (BP). The heparinization involves pretreatment of BP using …