The antithrombotic versus calcium antagonistic effects of polyethylene glycol grafted bovine pericardium
SC Vasudev, T Chandy… - Journal of biomaterials …, 1999 - journals.sagepub.com
Cardiovascular calcification, the formation of calcium phosphate deposits in cardiovascular
tissue, is a common end stage phenomenon affecting a wide variety of bioprosthesis. This …
tissue, is a common end stage phenomenon affecting a wide variety of bioprosthesis. This …
Elastin stabilization through polyphenol and ferric chloride combined treatment for the enhancement of bioprosthetic heart valve anticalcification
The lifetime of bioprosthetic heart valves (BHVs) is limited by the mechanical damage and
calcification. The major components of BHVs are collagen and elastin. Collagen could be …
calcification. The major components of BHVs are collagen and elastin. Collagen could be …
Comparison study of surface-initiated hydrogel coatings with distinct side-chains for improving biocompatibility of polymeric heart valves
Y Chen, Y Guo, X Li, Y Chen, J Wang, H Qian… - Biomaterials …, 2024 - pubs.rsc.org
Polymeric heart valves (PHVs) present a promising alternative for treating valvular heart
diseases with satisfactory hydrodynamics and durability against structural degeneration …
diseases with satisfactory hydrodynamics and durability against structural degeneration …
Neomycin and carbodiimide crosslinking as an alternative to glutaraldehyde for enhanced durability of bioprosthetic heart valves
J Leong, A Munnelly, B Liberio… - Journal of …, 2013 - journals.sagepub.com
Glutaraldehyde cross-linked porcine aortic valves, referred to as bioprosthetic heart valves
(BHVs), are often used in heart valve replacements. Glutaraldehyde does not stabilize …
(BHVs), are often used in heart valve replacements. Glutaraldehyde does not stabilize …
The effects of cross‐link density and chemistry on the calcification potential of diamine‐extended glutaraldehyde‐fixed bioprosthetic heart‐valve materials
D Bezuidenhout, A Oosthuysen… - Biotechnology and …, 2009 - Wiley Online Library
Despite indications that GA (glutaraldehyde)‐cross‐linked tissues remain prone to long‐
term degradation and calcification, it is still the reagent of choice in the fixation of …
term degradation and calcification, it is still the reagent of choice in the fixation of …
Mapping of glutaraldehyde‐treated bovine pericardium and tissue selection for bioprosthetic heart valves
D Simionescu, A Simionescu… - Journal of biomedical …, 1993 - Wiley Online Library
Glutaraldehyde‐crosslinked bovine pericardium is widely used in bioprosthetic heart valve
fabrication. In an attempt to set a scientific basis for more reproducible tissue selection, we …
fabrication. In an attempt to set a scientific basis for more reproducible tissue selection, we …
A synergistic strategy of dual-crosslinking and loading intelligent nanogels for enhancing anti-coagulation, pro-endothelialization and anti-calcification properties in …
M Hu, S Shi, X Peng, X Pu, X Yu - Acta Biomaterialia, 2023 - Elsevier
ABSTRACT Currently, glutaraldehyde (GA)-crosslinked bioprosthetic heart valves (BHVs)
still do not guarantee good biocompatibility and long-term effective durability for clinical …
still do not guarantee good biocompatibility and long-term effective durability for clinical …
A versatile drug-controlled release polymer brush hybrid non-glutaraldehyde bioprosthetic heart valves with enhanced anti-inflammatory, anticoagulant and anti …
Transcatheter heart valve replacement (THVR) is a novel treatment modality for severe heart
valves diseases and has become the main method for the treatment of heart valve diseases …
valves diseases and has become the main method for the treatment of heart valve diseases …
[HTML][HTML] Hybrid heart valves with VEGF-loaded zwitterionic hydrogel coating for improved anti-calcification and re-endothelialization
Q Tong, A Sun, Z Wang, T Li, X He, Y Qian, Z Qian - Materials Today Bio, 2022 - Elsevier
With the aging of the population in worldwide, valvular heart disease has become one of the
most prominent life-threatening diseases in human health, and heart valve replacement …
most prominent life-threatening diseases in human health, and heart valve replacement …
A novel crosslinking method for improved tear resistance and biocompatibility of tissue based biomaterials
Over 300,000 heart valve replacements are performed annually to replace stenotic and
regurgitant heart valves. Bioprosthetic heart valves (BHVs), derived from glutaraldehyde …
regurgitant heart valves. Bioprosthetic heart valves (BHVs), derived from glutaraldehyde …